Palliation of obstructive nephropathy due to malignancy

British Journal of Urology
K J HarringtonJ Waxman

Abstract

To conduct a prospective study of patients with malignant obstructive uropathy treated actively by percutaneous nephrostomy and J-J ureteric stents. Forty-two patients (27 men, 15 women, median age 62 years, range 29-83) with obstructive nephropathy secondary to malignancy underwent urinary diversion followed, where appropriate, by active treatment of the underlying cancer. The median survival of all patients was 133 (range 7-712) days. Seventeen patients (40%) survived for > 6 months and five (12%) for < 1 month. Patients who had received no prior therapy and for whom further therapeutic options were available were more likely to benefit from urinary diversion. In nine patients (21%) nephrostomy insertion failed to relieve renal failure. In 20 patients (48%) obstructive nephropathy recurred. The procedure was complicated by urinary tract or nephrostomy site infection in 16 patients, by septicaemia in six patients, by percutaneous urine leak in 13 patients and by pelvi-calyceal perforation in two patients, but not by haemorrhage or death. The median percentage of the patients' remaining life which was spent in hospital was 23.6% (range 2.2-100). Patients likely to benefit from nephrostomy were those for whom there were therapeu...Continue Reading

References

May 1, 1975·The Journal of Urology·E N BrinR M Weiss
Jan 1, 1979·Urologic Radiology·L EkelundS B Lundquist
Oct 11, 1975·Urology·J E FowlerA R Goldin
Jul 1, 1991·Gynecologic Oncology·G A FeuerJ G Boyce
May 1, 1988·American Journal of Obstetrics and Gynecology·J T SoperW T Creasman
Jan 1, 1988·European Urology·G JanetschekH Hetzel
Jan 1, 1988·Acta Obstetricia Et Gynecologica Scandinavica·H Pedersen, N Juul
Feb 1, 1973·Southern Medical Journal·H Grabstald, M McPhee
Oct 1, 1984·AJR. American Journal of Roentgenology·Z L Barbaric
Aug 1, 1984·American Journal of Obstetrics and Gynecology·V V BakerL A Walton
Aug 1, 1980·British Journal of Urology·B FallonD A Culp
Dec 1, 1980·Gynecologic Oncology·W J MannH M Shingleton
Jan 1, 1993·Clinical Oncology : a Journal of the Royal College of Radiologists·I J Kerby
Mar 1, 1993·British Journal of Obstetrics and Gynaecology·S KehoeH Earl

❮ Previous
Next ❯

Citations

Nov 29, 2001·Journal of Endourology·J KleinmannA Lindner
Apr 19, 2002·Journal of Endourology·Gary W Chien, Gary C Bellman
Nov 14, 1997·Journal of Endourology·M GallucciA Zaccara
Mar 1, 2005·Journal of Endourology·Bradley H RosenbergJeffrey A Triest
Dec 4, 2009·Journal of Endourology·Petros SountoulidesNikolaos Sofikitis
Dec 24, 2011·Journal of Endourology·Justin I FriedlanderArthur D Smith
Dec 15, 2012·Journal of Endourology·Ammara AbbasiKenneth Ogan
Mar 10, 2011·World Journal of Surgery·Kazuhiro MigitaYoriaki Kagebayashi
Oct 19, 2000·Cancer Investigation·N I Cherny, N Hiller
Apr 9, 2008·Journal of Pain and Symptom Management·Rodrigo DienstmannCarlos Gil Ferreira
May 15, 2007·The Journal of Urology·Lih-Ming WongAlexander G Pitman
Apr 3, 2009·BJU International·Andrew LienertStephen Mark
Apr 27, 2011·International Journal of Urology : Official Journal of the Japanese Urological Association·Yoshihiro KamiyamaYoichi Arai
Nov 11, 2005·The Journal of Urology·Anjali M Ganatra, Kevin R Loughlin
Mar 18, 1999·Hematology/oncology Clinics of North America·I Finlay
May 19, 2001·Best Practice & Research. Clinical Obstetrics & Gynaecology·H Singh
Dec 3, 2014·The Journal of Urology·Julia FiukJohn D Denstedt
Oct 16, 2014·International Urology and Nephrology·Sang Hoon SongBumsik Hong
Apr 10, 2009·New Directions for Youth Development·Reed W LarsonKathrin C Walker
Nov 8, 2018·Investigative and Clinical Urology·Ji Hyung YoonTaekmin Kwon
May 31, 2012·Current Opinion in Supportive and Palliative Care·Daniel Liberman, Michael McCormack
May 31, 2007·Annals of the Royal College of Surgeons of England·Oliver M JonesJ Basil J Fozard
Jul 3, 2013·Clinical Nuclear Medicine·Arthur ChoWon Jun Kang

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.