Palmitoleic acid calcium salt: a lubricant and bactericidal powder from natural lipids

Journal of Oleo Science
Yoshiaki YamamotoYoshimune Nonomura

Abstract

Palmitoleic acid is a promising bactericidal agent for cleansing products with alternative bactericidal abilities. In this study, we focus on the physical and biological activity of palmitoleic acid calcium salt (C16:1 fatty acid Ca salt) because it forms via an ion-exchange reaction between palmitoleic acid and Ca ions in tap water, and remains on the skin surface during the cleansing process. Here, we prepared C16:1 fatty acid Ca salt to investigate its crystal structure and physical and bactericidal properties. The Ca salt was a plate-shaped lamellar crystalline powder with a particle diameter of several micrometers to several tens of micrometers; it exhibited significant lubricity and alternative bactericidal activity against Staphylococcus aureus (S. aureus) and Propionibacterium acnes (P. acnes). We also examined other fatty acid Ca salts prepared from lauric acid (C12:0 fatty acid), palmitic acid (C16:0 fatty acid), and oleic acid (C18:1 fatty acid). The bactericidal activities and lubricity of the fatty acid Ca salts changed with the alkyl chain length and the degree of unsaturation. The C16:1 fatty acid Ca salt exhibited the strongest selective bactericidal ability among the four investigated fatty acid Ca salts. These...Continue Reading

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Citations

Sep 16, 2015·Journal of Oleo Science·Yoshiaki YamamotoYoshimune Nonomura
Oct 12, 2016·Biological & Pharmaceutical Bulletin·Kazuhiko NishimuraYutaka Itabashi
Jun 8, 2018·Journal of Oleo Science·Toshiya MorikawaYoshimune Nonomura
Jul 12, 2019·Journal of Oleo Science·Minako OkukawaYoshimune Nonomura
Jun 24, 2019·Lipids in Health and Disease·Marta Solà Marsiñach, Aleix Pellejero Cuenca
Jun 11, 2019·Journal of Oleo Science·Maki Miura, Yoshimune Nonomura
Jan 31, 2017·ACS Omega·Yoshiaki YamamotoYoshimune Nonomura
Aug 11, 2021·Journal of Oleo Science·Minako OkukawaYoshimune Nonomura

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