Pancreatic blastomatous tumor in a child responding to therapy used for hepatoblastoma: case report and review of the literature

Medical and Pediatric Oncology
E R MorganF J Gonzalez-Crussi

Abstract

A case is reported of a 7-year old girl diagnosed with initially inoperable metastatic embryonic pancreatic tumor, which showed a significant clinical response to chemotherapeutic agents commonly used to treat hepatoblastoma. This regimen was selected because certain histologic features of the tumor demonstrated characteristics seen in hepatic tissue. After two course of chemotherapy (cis-platinum and adriamycin), there was a significant reduction of the primary mass, and it was completely resected, although the tumor subsequently recurred in the metastatic, unoperated site. The embryological relationship between the tumor in this patient and hepatoblastoma, as well as the literature concerning treatment in pediatric pancreatoblastic tumors are reviewed. Complete eradication of tumor appears to be necessary for cure.

References

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Citations

Dec 10, 2009·Pediatric Blood & Cancer·Patrizia Dall'ignaUNKNOWN TREP Group
Jul 16, 2015·Pediatric Surgery International·Omar NasherAgostino Pierro
Jun 24, 2011·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·Ewa BienAndrea Ferrari
Nov 3, 2006·Pancreas·Edward L Bradley
Apr 30, 2002·Medical and Pediatric Oncology·Anjali SharathkumarElla Onikul
Jan 2, 2007·Pancreas·Liping Cao, Daren Liu
Jun 27, 2021·Pediatric Blood & Cancer·Ewa BienYves Reguerre

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