Pancreatic cancer: A critical review of dietary risk

Nutrition Research
Asmaa A Salem, Gerardo G Mackenzie

Abstract

Pancreatic cancer is a deadly disease. It is estimated that about 90% of pancreatic cancer cases are due to environmental risk factors. Among these, approximately 50% of pancreatic cancer cases may be attributed to diet, which is largely modifiable. Given this large attribution to diet, there have been numerous epidemiological studies assessing the risk of various dietary factors on the incidence of pancreatic cancer. However, many of these studies present conflicting and/or inconclusive findings. The objective of this review is two-fold: (a) to summarize the current evidence on the association between various dietary factors and the risk of developing pancreatic cancer and (b) to discuss what additional studies are needed to better elucidate the role of diet as a potential risk factor for pancreatic cancer. We summarized the evidence by using data primarily from meta-analyses and pooled analysis when available, focusing on the most studied nutrients, foods, and dietary patterns. We observed that, while the association between individual nutrients and pancreatic cancer risk have been heavily studied, the evidence is mostly conflicting and inconclusive. In contrast, the evidence of certain associations among dietary patterns and...Continue Reading

Citations

Dec 19, 2019·Nature Reviews. Cancer·Susan E Steck, E Angela Murphy
Nov 28, 2020·Biochimica Et Biophysica Acta. Reviews on Cancer·Jia DongLiang Liu
Nov 13, 2020·Nutrición hospitalaria·Ayşegül Bükülmez, Lütfi Molon
Mar 14, 2021·Seminars in Cancer Biology·Violet Kayamba
Jul 6, 2020·Experimental and Molecular Pathology·Jing ZhouJianing Xi
Feb 24, 2021·Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology·Li-Wei ShiGuo-Chao Zhong
Aug 10, 2021·World Journal of Gastroenterology : WJG·Jian-Xiong HuFeng Gao
Oct 10, 2021·Cancer Epidemiology·Ahmad Naghibzadeh-TahamiAli Akbar Haghdoost

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