PMID: 26320426Sep 1, 2015Paper

Pancreatic Cancer: Pathogenesis and Diagnosis

Asian Pacific Journal of Cancer Prevention : APJCP
Vedat Goral

Abstract

Pancreatic cancer is a fatal malignancies which is predominantly seen in men and at advanced age (40-85 years) and has an aggressive course. Its frequency is gradually increasing over the past years. It accounts for 2% of all cancers and 5% of cancer-related deaths. Pancreatic cancer takes the first place among asymptomatic cancers. Ninety percent of cases are adenocarcinomas. Ten percent of the patients have a familial disposition. The disease is very difficult to detect as it has no early signs and spreads rapidly to surrounding organs is one of the most deadly types of cancer. Pancreatic cancer may result from hereditary germline or somatic acquired mutations in cancer-related genes and mutations also cause cancer progression and metastasis.

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Citations

Sep 28, 2018·Journal of Cellular Biochemistry·Fan JiangChi-Z Zhou
Jul 25, 2019·Laboratory Medicine·Wang Gu, Zhong Tong
Dec 31, 2016·International Journal of Oncology·Yun HeZhenzhai Cai
Nov 23, 2019·Cytokine & Growth Factor Reviews·Zhiqiang LiJan G D'Haese
Dec 29, 2020·Technology in Cancer Research & Treatment·ZhiYu Zhao, Wei Liu
Mar 7, 2021·Journal of Personalized Medicine·Beste TuranliRaghu Sinha
Jun 8, 2021·Virology : Research and Treatment·Prapti H ModyJuliet V Spencer
Jul 10, 2021·World Journal of Gastroenterology : WJG·Michail GalanopoulosChristos Liatsos
Sep 2, 2021·American Journal of Physiology. Gastrointestinal and Liver Physiology·Wenchong Song, Chengjian Shi
Dec 1, 2021·Langenbeck's Archives of Surgery·Satoshi OkuboJunichi Shindoh

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