PMID: 6104406Apr 1, 1980Paper

Pancreatic hormonal release after glucose and arginine administration in anaesthetized pigs

Acta Endocrinologica
S GustavssonG Lundqvist

Abstract

Somatostatin, pancreatic polypeptide (PP), insulin and glucagon were measured in pancreatic venous effluent and in mixed venous blood of anaesthetized pigs. After stimulation of insulin release with glucose and arginine, respectively, a prompt decrease in PP levels was found in pancreatic venous blood. Somatostatin declined after glucose administration but was unaffected by arginine. The changes in PP and somatostatin levels were not evident in systemic blood. The present results emphasize the advantage of selective sampling of pancreatic venous blood in studies on the possible interactions between pancreatic hormones. The marked decrease in PP seen after stimulation of insulin release in the present study, indicates that PP should be included together with somatostatin in further studies on pancreatic hormonal interplay.

Citations

Apr 1, 1989·Scandinavian Journal of Clinical and Laboratory Investigation·B VonenP Burhol
Apr 1, 1989·Scandinavian Journal of Clinical and Laboratory Investigation·B VonenP Burhol
Jan 1, 1982·Upsala Journal of Medical Sciences·S Gustavsson, G Lundqvist
Jun 23, 2007·Diabetes & Metabolism·D DufraneJ C Henquin
Apr 1, 1992·Scandinavian Journal of Clinical and Laboratory Investigation·B VonenP G Burhol

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