PMID: 6991821Jan 1, 1980Paper

Pancreatic polypeptide cell hyperplasia with and without watery diarrhea syndrome

Journal of Surgical Oncology
T TomitaF A Mantz

Abstract

Two cases of pancreatic polypeptide cell hyperplasia were obtained by operation. The first case exhibited adenocarcinoma of the stomach with metastases to the neck lymph nodes and pancreatic polypeptide hypersecretion. Pancreatic polypeptide cell hyperplasia was confirmed by the immunoperoxidase method and by the elevated level of pancreatic polypeptide in the pancreatic extracts and in the circulating blood. There was no watery diarrhea syndrome. The second case presented with persistent watery diarrhea of two and one-half year duration, and the resected pancreas contained extremely large atypical islets, exclusively composed of pancreatic polypeptide cells. It is speculated that in some cases pancreatic polypeptide oversecretion may be causative for pseudo-Verner-Morrison syndrome in the absence of ulcer of carcinoma in the upper gastrointestinal tract.

References

Jan 22, 1977·Lancet·T E AdrianR C Russell
Dec 2, 1978·Lancet·L OrciA Perrelet
Jan 1, 1978·Scandinavian Journal of Gastroenterology·G LundqvistR E Chance
Feb 1, 1978·The Journal of Clinical Endocrinology and Metabolism·C BordiL Orci
Mar 1, 1978·The Journal of Clinical Investigation·T W SchwartzF Stadil
Apr 1, 1978·The American Journal of Digestive Diseases·J D Gardner
Jan 1, 1978·The Journal of Clinical Endocrinology and Metabolism·J MarcoM L Villanueva
Jan 1, 1970·The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society·P K Nakane
Dec 1, 1973·General and Comparative Endocrinology·R L HazelwoodH G Pollock
Dec 1, 1968·Endocrinology·J R KimmelR L Hazelwood

❮ Previous
Next ❯

Citations

Feb 5, 2002·Peptides·Cesare BordiSilvia Pizzi
Aug 12, 2010·Veterinary Clinical Pathology·Janice A Cruz CardonaMatti Kiupel
Jul 1, 1989·Journal of Veterinary Internal Medicine·C A ZerbeT M O'Dorisio
Oct 6, 2006·Journal of Clinical Pathology·R AlbazazC S Verbeke
Jan 1, 2008·Case Reports in Gastroenterology·Vera AmrillevaVolker Fendrich
Jan 20, 2011·World Journal of Gastroenterology : WJG·Debra OuyangRun Yu
Jan 1, 1984·Virchows Archiv. B, Cell Pathology Including Molecular Pathology·T TomitaV Doull
Apr 1, 1988·Pathology, Research and Practice·G Klöppel, P U Heitz
Dec 18, 2007·Biochimica Et Biophysica Acta·Xiaolei XieJianguo Ji
Dec 1, 1996·Baillière's Clinical Gastroenterology·S K ParkT M O'Dorisio
Sep 1, 1987·Seminars in Oncology·H S Mekhjian, T M O'Dorisio
Aug 9, 2002·Pathology International·Tatsuo Tomita
Jan 1, 1987·Critical Reviews in Clinical Laboratory Sciences·Y F Shiau
May 29, 1987·The American Journal of Medicine·G J Krejs
Nov 1, 1981·General and Comparative Endocrinology·T Tomita, H G Pollock

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.