A comparative study of arteriography and pancreatic venous sampling (PVS) was performed in 55 patients. Twenty-seven patients with Zollinger-Ellison syndrome, 24 with insulinomas, and 4 control subjects underwent arteriography and PVS (for pancreatic hormonal radioimmunoassays) in an attempt to localize a suspected endocrine tumor. Accurate tumor localization was achieved by arteriography in 13% of the cases of gastrinoma and 29% of the cases of insulinoma. Although arteriographic signs could be described retrospectively in 62% of insulinomas, erroneous localization was relatively frequent. In contrast, localization by PVS was successful in 36 out of the 38 patients who underwent surgery; false-negative results were obtained in two patients, but in no case did PVS result in false localization. In 27% of insulinomas and 43% of gastrinomas, gross examination during surgery was negative but microscopic tumors were identified.
Prospective study of gastrinoma localization and resection in patients with Zollinger-Ellison syndrome
Curative resection of multiple gastrinomas aided by selective arterial secretin injection test and intraoperative secretin test
Resolved and unresolved controversies in the surgical management of patients with Zollinger-Ellison syndrome
Endoscopic ultrasonography and somatostatin receptor scintigraphy in the preoperative localisation of insulinomas and gastrinomas
CT, endoscopic sonography, and a combined protocol for preoperative evaluation of pancreatic insulinomas
Preoperative imaging versus intraoperative localization of tumors in adult surgical patients with hyperinsulinemia: a multicenter study of 338 patients
Is preoperative radiographic localization of islet cell tumors in patients with insulinoma necessary?
Pathologic aspects of gastrinomas in patients with Zollinger-Ellison syndrome with and without multiple endocrine neoplasia type I
Localization of small islet-cell tumors. Preoperative and intraoperative ultrasound, computed tomography, arteriography, digital subtraction angiography, and pancreatic venous sampling
Hyperinsulinism in children: diagnostic value of pancreatic venous sampling correlated with clinical, pathological and surgical outcome in 25 cases
Operative tumour yield obviates preoperative pancreatic tumour localization in multiple endocrine neoplasia type 1
Prospective study of provocative angiograms to localize functional islet cell tumors of the pancreas
Localization of insulinoma by laparoscopic infragastric inspection of the pancreas and contact ultrasonography
Accurate localization of insulinoma using percutaneous transhepatic portal venous sampling--usefulness of simultaneous measurement of plasma insulin and glucagon levels
Usefulness of EUS-guided fine needle aspiration (EUS-FNA) in the diagnosis of functioning neuroendocrine tumors
Adenoma, Islet Cell
Islet Cell Adenoma arises in the islet cells, which are insulin producing cells of the pancreas. These tumors can be either malignant or benign. Discover the latest research on Islet Cell Adenoma here.