Panic Disorder Induced by the Coronavirus Disease Pandemic in a Patient with Organic Mood Disorder Successfully Treated with Vortioxetine

Case Reports in Psychiatry
Reiji YoshimuraAtsuko Ikenouchi

Abstract

We present a case of panic disorder induced by the coronavirus disease (COVID-19) pandemic in a patient with an organic mood disorder. The patient was a 62-year-old woman with mild mood swings and reduced motivation and volition caused by a traumatic brain injury after a traffic accident. She was maintained on carbamazepine (600 mg/day). When the COVID-19 outbreak occurred in Japan, she developed concerns regarding the illness and complained of multiple episodes of panic attacks. Further, her depressive symptoms worsened. Thus, vortioxetine was added to the ongoing CBZ treatment. Four weeks after initiating vortioxetine treatment, the symptoms of panic disorder and depressive state were ameliorated. The present case suggests that vortioxetine augmentation can improve symptoms of depressive state and panic disorder induced by the COVID-19 pandemic.

References

Feb 2, 2011·The British Journal of Psychiatry : the Journal of Mental Science·Roland M JonesPamela J Taylor
Apr 13, 2012·Drug Metabolism and Disposition : the Biological Fate of Chemicals·Mette G HvenegaardLars Dalgaard
May 13, 2017·Pharmacological Reports : PR·Magdalena Sowa-KućmaMagdalena Koperny
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Dec 1, 2017·Clinical Pharmacokinetics·Grace ChenGeorge Nomikos
May 24, 2020·The Lancet. Psychiatry·Victor Pereira-SanchezMariana Pinto da Costa

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