Paper-Based Systems for Point-of-Care Biosensing

Journal of Laboratory Automation
Sherine F CheungDaniel T Kamei

Abstract

Paper-based systems have been widely investigated for developing point-of-care devices because of their simplicity, affordability, and ease of use. Recent advances have resulted in paper systems that have progressed beyond the historical "single-strip" format and allow for a larger range of functions. This review provides a summary of the advances that have been made to improve the utility of paper-based diagnostic tests for biosensing. Specifically, techniques for designing paper devices, including different geometries and chemical patterning to control fluid flow, are discussed. This review also examines novel approaches to improve paper-based assay sensitivities, such as sample preconcentration, signal amplification at the detection zone, and electrochemical methods.

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Apr 17, 2016·Journal of Pharmacological and Toxicological Methods·Alison ObergrussbergerNiels Fertig
Dec 14, 2016·Analytical Chemistry·Samiksha NayakSamuel K Sia
Jul 22, 2015·Journal of Laboratory Automation·Xianting Ding
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Nov 14, 2020·Analytical Methods : Advancing Methods and Applications·Jin ZhaoZhixu He

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Methods Mentioned

BETA
pregnancy test
Assay
enzyme-linked immunoassay
electrophoresis
surface plasmon resonance
biosensing

Software Mentioned

MATLAB
ImageJ

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