Abstract
Papillary renal cell carcinoma may display some unusual morphologic variations, including diffuse oncocytic change not otherwise specified, oncocytic change associated with an inverted nuclear pattern or nonoverlapping low-grade nuclei, low-grade spindle cells, and diffuse clear cells. Tumors comprised predominantly of thyroid-like follicles and inspissated eosoinophilic, colloid-like secretions (thyroid-like follicular carcinoma of the kidney) have been recently recognized. We report herein an unusual renal carcinoma that displayed diffuse clear cells, papillary architecture, foamy histiocytes, psammomatous calcifications, and large areas (approximately 20% of tumor volume) with thyroid macrofollicular-like structures and eosinophilic, colloid-like secretions. The tumor was diffusely positive for alpha-methylacyl-CoA racemase, cytokeratin 7 and CD10, and was entirely negative for CD15, thyroglobulin, thyroid-transcription factor-1, TFE3, and renal cell carcinoma antigen. Fluorescence in situ hybridization using centromeric DNA probes for chromosomes 7, 17, 3, and 3p25 showed gains only in chromosome 7 and no other aberrations. The tumor was accordingly classified as an unusual morphologic variation of papillary renal cell carc...Continue Reading
References
Oct 1, 1996·Urology·S K AngellF S Freiha
Jun 1, 1997·The American Journal of Surgical Pathology·M B AminD S Schultz
Aug 25, 1999·Histopathology·L FüzesiG Jakse
Jul 5, 2001·The American Journal of Pathology·P ArganiM Ladanyi
Feb 23, 2002·The American Journal of Surgical Pathology·Mahul B AminMani Menon
Dec 3, 2002·The American Journal of Surgical Pathology·Pedram ArganiMarc Ladanyi
Apr 30, 2003·The American Journal of Surgical Pathology·John C ChevilleMichael L Blute
May 27, 2003·The American Journal of Surgical Pathology·Pedram ArganiMarc Ladanyi
Aug 30, 2003·Archives of Pathology & Laboratory Medicine·M E SalamaM DePeralta-Venturina
Apr 26, 2005·Clinics in Laboratory Medicine·Ming ZhouCristina Magi-Galluzzi
Apr 26, 2005·Clinics in Laboratory Medicine·Pedram Argani, Marc Ladanyi
Jun 21, 2005·European Urology·Tomas GudbjartssonGudmundur V Einarsson
Dec 6, 2005·The American Journal of Surgical Pathology·Marine LefèvreYves Allory
Jan 26, 2006·The American Journal of Surgical Pathology·Satish K TickooMahul B Amin
Mar 4, 2006·Seminars in Diagnostic Pathology·Brian F Skinnider, Mahul B Amin
Mar 16, 2006·The American Journal of Surgical Pathology·Soo Jin JungJae Y Ro
May 16, 2006·European Urology·Vincenzo FicarraWalter Artibani
May 30, 2006·Annals of Diagnostic Pathology·Ondrej HesGuido Martignoni
Oct 13, 2006·Pathology, Research and Practice·Kien T MaiJohn P Veinot
Aug 2, 2007·The American Journal of Surgical Pathology·Pedram ArganiMarc Ladanyi
Aug 21, 2007·Virchows Archiv : an International Journal of Pathology·William SterlacciMikuz Gregor
Oct 24, 2007·Human Pathology·Lakshmi P KunjuRajal B Shah
Feb 2, 2008·Cancer·Vitaly MargulisChristopher G Wood
Feb 22, 2008·CA: a Cancer Journal for Clinicians·Ahmedin JemalMichael J Thun
Jul 3, 2008·The American Journal of Surgical Pathology·Stefano GobboLiang Cheng
Jul 23, 2008·International Journal of Urology : Official Journal of the Japanese Urological Association·Davis P ViprakasitThomas C Keeler
Aug 2, 2008·The American Journal of Surgical Pathology·Pedram ArganiAnil V Parwani
Sep 10, 2008·The American Journal of Surgical Pathology·Stefano GobboLiang Cheng
Nov 26, 2008·Human Pathology·Liang ChengRodolfo Montironi
Dec 3, 2008·The American Journal of Surgical Pathology·Mahul B AminJonathan I Epstein
Mar 6, 2009·Pathology International·Bong-Hee ParkYong Mee Cho
Citations
Jul 4, 2013·Diagnostic Pathology·Metka VolavšekGregor Mikuz
Dec 18, 2013·Abdominal Imaging·R A VicensR Vikram
Aug 19, 2014·Case Reports in Pathology·William W WuLisa Shane
Nov 14, 2014·Pathology·Abhijit ChouguleBrusabhanu Nayak
Nov 21, 2012·Diagnostic Cytopathology·Jasreman DhillonSavitri Krishnamurthy
Mar 11, 2015·Seminars in Diagnostic Pathology·Brett Delahunt, John R Srigley
Sep 17, 2016·Cancer Cytopathology·Xiaoqi Lin
Mar 23, 2017·Medicine·Hui WangGang Li
Dec 14, 2011·International Journal of Surgical Pathology·Hatim A KhojaSara Almaiman
Oct 5, 2018·The American Journal of Surgical Pathology·Leal HerlitzJesse K McKenney
May 8, 2019·International Braz J Urol : Official Journal of the Brazilian Society of Urology·Lisieux Eyer de JesusSamuel Dekermacher
Aug 18, 2012·Virchows Archiv : an International Journal of Pathology·Lara AlessandriniFiliberto Zattoni
Feb 3, 2021·Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc·Kiril TrpkovOndrej Hes