Papillary squamous cell carcinoma of the uterine cervix: report of a case with HPV 16 DNA and brief review

Gynecologic Oncology
C W OllayosI S Ali

Abstract

Papillary squamous cell carcinoma (PSCC) of the uterine cervix is a rare variant of squamous cell carcinoma (SCC). It is characterized by a papillary architecture and markedly atypical epithelium. Invasion and metastasis have been reported. We report a case of PSCC in a 72-year-old woman who subsequently tested positive for HPV 16. To our knowledge, this is the first report of HPV typing in a case of PSCC. Our finding of a high-risk HPV type in PSCC may help explain why PSCC has been reported to have a clinical course similar to that of nonpapillary SCC.

Citations

Sep 16, 2011·The Journal of Obstetrics and Gynaecology Research·Bernhard NiederleArnd Honig
Dec 2, 1998·APMIS : Acta Pathologica, Microbiologica, Et Immunologica Scandinavica·E NakamuraT Manabe
Jul 25, 2000·International Journal of Gynecological Pathology : Official Journal of the International Society of Gynecological Pathologists·U BrinckL Füzesi
Jul 27, 2005·Journal of Lower Genital Tract Disease·Peter A DrewDaylene L Ripley
Jun 1, 2010·Pathology Oncology Research : POR·Tito Silvio PatrelliGiovanni Battista Nardelli
Apr 12, 2002·Acta Obstetricia Et Gynecologica Scandinavica·Toshio FujimotoSeiichiro Fujimoto

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