PMID: 3773569Dec 1, 1986Paper

Papillary thyroid cancer treated at the Mayo Clinic, 1946 through 1970: initial manifestations, pathologic findings, therapy, and outcome

Mayo Clinic Proceedings
W M McConaheyW F Taylor

Abstract

We performed a retrospective study of 859 patients with papillary thyroid cancer, who had received their primary treatment at the Mayo Clinic during the period 1946 through 1970. The maximal follow-up was 39 years. All but 2 patients underwent a thyroid operation; 319 (37%) had metastatic cervical nodes. Of the 800 patients without distant metastatic lesions on initial examination who underwent a potentially curative surgical procedure, postoperatively 7% had nodal metastatic lesions, 6% had a local tumor recurrence, and 5% had a distant metastatic lesion. In patients who had intrathyroidal tumors initially, postoperative local recurrences or distant metastatic lesions resulted in a 10-year cancer mortality of 17 and 41%, respectively; in those with extrathyroidal tumors, postoperative recurrences were associated with significantly higher death rates. Death from thyroid cancer was highly associated with the following factors: age more than 50 years, male sex, tumor size, tumor grade, initial extent of disease, and absence of Hashimoto's disease. Earlier studies of Mayo patients treated between 1926 and 1960 described no deaths due to thyroid cancer in patients with occult tumors (1.5 cm or less). Four such patients were identif...Continue Reading

References

Aug 1, 1979·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·D P ByarM van Glabbeke
Sep 1, 1975·Cancer·K O Franssila
Dec 1, 1984·Mayo Clinic Proceedings·R G WatsonW F Taylor
Jun 1, 1983·The Journal of Clinical Endocrinology and Metabolism·N A SamaanC E Litton
Jan 1, 1982·Virchows Archiv. A, Pathological Anatomy and Histology·J Tscholl-Ducommun, C E Hedinger
Oct 1, 1981·American Journal of Surgery·H J WaneboD L Kaiser
Jan 1, 1960·The Journal of Clinical Endocrinology and Metabolism·L B WOOLNERF R KEATING
Dec 1, 1961·The Journal of Clinical Endocrinology and Metabolism·R N HIRABAYASHI, LINDSAYS

❮ Previous
Next ❯

Citations

Jun 1, 1996·Journal of Surgical Oncology·T KobayashiM Monden
Feb 11, 1998·Journal of Surgical Oncology·M NoguchiK Miwa
Dec 20, 1996·International Journal of Cancer. Journal International Du Cancer·J A CalifanoD Sidransky
Apr 17, 2001·Head & Neck·J D LinT C Chao
Apr 5, 2002·Head & Neck·Luiz Paulo Kowalski, João Gonçalves Filho
Mar 1, 1994·Head & Neck·T V McCaffreyI D Hay
Jan 1, 1995·Head & Neck·M L Collazo-ClavellN E Maragos
Mar 1, 1993·Journal of Surgical Oncology·Y KrauszB Glaser
Aug 1, 1995·Journal of Surgical Oncology·A EroğluE Yildirim
Jul 1, 1994·European Journal of Nuclear Medicine·S M Bakheet, M M Hammami
Jul 1, 1994·World Journal of Surgery·S NoguchiH Kawamoto
Jan 1, 1994·Journal of Neuro-oncology·B M BiswalG K Rath
Jan 1, 1995·Journal of Cancer Research and Clinical Oncology·L MasmiquelJ Mesa
Oct 1, 1988·World Journal of Surgery·J K HarnessR E Burney
Jan 1, 1996·Endocrine Pathology·Armando Gamboa-DominguezArturo Angeles-Angeles
Oct 3, 2007·Investigational New Drugs·Athanassios ArgirisSally E Carty
Jan 2, 2014·Indian Journal of Otolaryngology and Head and Neck Surgery : Official Publication of the Association of Otolaryngologists of India·Nikhil NanjappaDhananjay Kotasthane
Feb 1, 1988·European Journal of Cancer & Clinical Oncology·J F HammingB M Goslings
May 2, 2006·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·Karl SegalAron Popovtzer
Jun 6, 2007·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·Sevim Turanli
Feb 23, 2010·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·Sang Hyuk LeeDong Hoon Kim
Apr 25, 2000·American Journal of Surgery·T NishidaT Hashimoto
Jan 5, 2001·The Surgical Clinics of North America·R B Lim, J H Wong

❮ Previous
Next ❯

Related Concepts

Related Feeds

Autoimmune Thyroiditis

Autoimmune thyroiditis is an inflammatory disease of thyroid gland due to autoimmune responses leading to lymphocytic infiltration of the gland. It is characterized by the presence of circulating thyroid antigen-specific T-cells and thyroid autoantibodies. Discover the latest research on autoimmune thyroiditis here.