Papillary thyroid carcinoma with exuberant nodular fasciitis-like stroma: treatment outcome and prognosis

The Journal of Laryngology and Otology
S BasuA M Borges

Abstract

Papillary thyroid carcinoma with nodular fasciitis-like stroma (PTC-NFS) is one of the extremely rare variants of papillary thyroid carcinoma. To date, the majority of reported cases have been published in the surgical pathology and cytopathology literature, addressing the diagnostic difficulties posed by the condition's extensive, reactive stromal proliferation. Because of the rarity of PTC-NFS among papillary thyroid carcinoma variants, it has been unexplored from a clinical viewpoint. A MEDLINE search on the clinical course, role of radioiodine, treatment outcome and long term follow up of this disease yielded no result.We report the clinicoradiologic and histopathologic profile, together with post-treatment long term follow up, in a 35-year-old woman harbouring this rare entity. To the best of our knowledge, this is the first report of a five-year follow up of this rare variant of PTC following total thyroidectomy and radioiodine treatment. Our follow-up findings reiterate the disease's favourable clinical course when managed in the same manner as a classical, differentiated papillary carcinoma of the thyroid, akin to that predicted by the pathologists, and emphasize the importance of differentiating PTC-NFS as a separate e...Continue Reading

Citations

Aug 13, 2011·Thyroid : Official Journal of the American Thyroid Association·Soo Youn BaeJee Soo Kim
Apr 1, 2010·Journal of Medical Ultrasonics·Kwang Woo LeeMee Kyoung Kim
Jan 31, 2008·Diagnostic Cytopathology·Isabel Irene Rama LealFrederico Sérgio Luis de Castro Montenegro
Dec 21, 2010·Advances in Anatomic Pathology·Elham Khanafshar, Ricardo V Lloyd
Mar 31, 2010·Endocrine Practice : Official Journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists·Ali B KhalilRichard Creel
Oct 29, 2011·Ear, Nose, & Throat Journal·Bevinahalli N NandeeshIsha Garg
Feb 11, 2015·International Journal of Surgical Pathology·Paula S Ginter, Theresa Scognamiglio
Apr 16, 2020·Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc·David SusterSaul Suster
Oct 8, 2016·Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc·Caterina RebecchiniMassimo Bongiovanni

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