Parabronchial smooth muscle cells and alveolar myofibroblasts in lung development

Birth Defects Research. Part C, Embryo Today : Reviews
Namjin Kim, Thiennu H Vu

Abstract

Epithelial-mesenchymal interactions and extracellular matrix remodeling are key processes of embryonic lung development. Lung smooth muscle cells, which are derived from the mesenchyme, form a sheath around bronchi and blood vessels. During lung organogenesis, smooth muscle differentiation coincides with epithelial branching morphogenesis and closely follows developing airways spatially and temporally. The precise function of parabronchial smooth muscle (PBSM) cells in healthy adult lung remains unclear. However, PBSM may regulate epithelial branching morphogenesis during lung development by the induction of mechanical stress or through regulation of paracrine signaling pathways. Alveolar myofibroblasts are interstitial contractile cells that share features and may share an origin with smooth muscle cells. Alveolar myofibroblasts are essential for secondary septation, a process critical for the development of the gas-exchange region of the lung. Dysregulation of PBSM or alveolar myofibroblast development is thought to underlie the pathogenesis of many lung diseases, including bronchopulmonary dysplasia, asthma, and interstitial fibrosis. We review the current understanding of the regulation of PBSM and alveolar myofibroblast de...Continue Reading

References

Dec 1, 1978·The Anatomical Record·C Vaccaro, J S Brody
May 1, 1992·American Journal of Respiratory Cell and Molecular Biology·J Roman, J A McDonald
Mar 1, 1992·Kidney International·G Gabbiani
Mar 1, 1991·Experimental Lung Research·A A Ten Have-Opbroek
Dec 1, 1990·American Journal of Respiratory Cell and Molecular Biology·J J MitchellJ Woodcock-Mitchell
Aug 1, 1990·Differentiation; Research in Biological Diversity·K O LeslieR B Low
Jul 1, 1989·Experimental Lung Research·A NoguchiR P Mecham
Jan 1, 1984·Annual Review of Physiology·P H Burri
Aug 1, 1994·The European Respiratory Journal·M P SparrowH W Mitchell
Nov 1, 1995·American Journal of Respiratory and Critical Care Medicine·K OhtaT E King
May 1, 1995·American Journal of Respiratory Cell and Molecular Biology·W V CardosoJ S Brody
Nov 1, 1994·Canadian Journal of Physiology and Pharmacology·A J Halayko, N L Stephens
Sep 6, 1993·FEBS Letters·P StrasserJ V Small
Aug 5, 1996·Biochemical and Biophysical Research Communications·K UraseT Momoi
Sep 1, 1996·Developmental Dynamics : an Official Publication of the American Association of Anatomists·W V CardosoM C Williams
Sep 19, 1998·Developmental Biology·W Y ParkW V Cardoso
Sep 23, 1998·The International Journal of Biochemistry & Cell Biology·R B Low, S L White
Oct 13, 1998·Current Biology : CB·C V PepicelliA P McMahon
Jan 23, 1999·Nature Genetics·K SekineS Kato
Apr 1, 1999·American Journal of Respiratory Cell and Molecular Biology·R B LowS L White
Jun 29, 2000·American Journal of Respiratory Cell and Molecular Biology·K T Nakamura, P B McCray
Jun 29, 2000·American Journal of Respiratory Cell and Molecular Biology·J C SchittnyM P Sparrow
Feb 22, 2001·Annual Review of Physiology·W V Cardoso
Jul 18, 2001·Journal of Applied Physiology·C Y Seow, J J Fredberg
Jul 27, 2002·Developmental Biology·Changgong LiParviz Minoo
Aug 10, 2002·American Journal of Physiology. Lung Cellular and Molecular Physiology·F DemayoJ S Torday
Sep 21, 2002·Developmental Dynamics : an Official Publication of the American Association of Anatomists·Christelle CorauxDominique Gaillard
Feb 1, 2003·Trends in Cell Biology·Pao-Tien Chuang, Andrew P McMahon
Jun 5, 2003·Developmental Biology·Molly WeaverBrigid L M Hogan
Jun 20, 2003·Nature·Takayoshi SakaiKenneth M Yamada
Oct 1, 2003·Respiratory Physiology & Neurobiology·Malcolm P Sparrow, Jasmine P Lamb
Jan 27, 2004·American Journal of Respiratory and Critical Care Medicine·Wayne Mitzner
Jan 30, 2004·Annual Review of Medicine·Victor J ThannickalFernando J Martinez
Feb 24, 2004·Annual Review of Physiology·John M Shannon, Brian A Hyatt
Jun 23, 2004·Development, Growth & Differentiation·Sussie DalvinT Bernard Kinane
Aug 12, 2004·Developmental Dynamics : an Official Publication of the American Association of Anatomists·Leigh-Anne D MillerJeffrey A Whitsett

❮ Previous
Next ❯

Citations

Nov 10, 2009·American Journal of Physiology. Lung Cellular and Molecular Physiology·Keli XuSean E Egan
Jun 2, 2007·American Journal of Respiratory Cell and Molecular Biology·Marta SantosJorge Correia-Pinto
Dec 17, 2009·Pediatric Research·Beth J AllisonStuart B Hooper
Oct 27, 2006·Proceedings of the American Thoracic Society·Stephen I RennardOlaf Holz
Dec 21, 2007·Proceedings of the American Thoracic Society·Kameswara Rao BadriLucia Schuger
Sep 14, 2010·Current Opinion in Cell Biology·Ryan S GrayAndrew J Ewald
Dec 20, 2008·Developmental Dynamics : an Official Publication of the American Association of Anatomists·Lan YiXin Sun
Dec 25, 2012·The American Journal of Pathology·Biao HuSem H Phan
Jan 22, 2011·Korean journal of pediatrics·Chang Won Choi
Apr 16, 2016·American Journal of Respiratory Cell and Molecular Biology·Manuela FunkeAndrew M Tager
Apr 8, 2017·Developmental Dynamics : an Official Publication of the American Association of Anatomists·Elie El AghaSaverio Bellusci
Mar 25, 2017·American Journal of Physiology. Lung Cellular and Molecular Physiology·Rachel M MedalLawrence S Prince
Mar 11, 2015·Molecular and Cellular Biology·Akiko SuzukiJunichi Iwata
Dec 19, 2007·The Anatomical Record : Advances in Integrative Anatomy and Evolutionary Biology·Renée DickieAkira Tsuda
Nov 16, 2018·Frontiers in Genetics·Lawrence S Prince
Jan 17, 2012·American Journal of Physiology. Lung Cellular and Molecular Physiology·Huiping LiYongjun Zhang
Aug 19, 2017·American Journal of Physiology. Lung Cellular and Molecular Physiology·Kazuyuki TsujinoDean Sheppard
Apr 6, 2017·American Journal of Respiratory Cell and Molecular Biology·Matthias C KuglerJohn S Munger
Mar 25, 2016·Journal of Developmental Biology·Lucie JeannotteKim Landry-Truchon
Oct 31, 2017·Current Pathobiology Reports·David M Habiel, Cory M Hogaboam
Dec 8, 2015·American Journal of Physiology. Lung Cellular and Molecular Physiology·Aline VuckovicJacques C Jani
Nov 30, 2019·Orphanet Journal of Rare Diseases·C Barazzone-ArgiroffoI Ruchonnet-Métrailler
Jul 31, 2013·American Journal of Physiology. Lung Cellular and Molecular Physiology·Annie R A McDougallMegan J Wallace

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.