Paradigms in isotope dilution mass spectrometry for elemental speciation analysis

Analytica Chimica Acta
Juris Meija, Zoltán Mester

Abstract

Isotope dilution mass spectrometry currently stands out as the method providing results with unchallenged precision and accuracy in elemental speciation. However, recent history of isotope dilution mass spectrometry has shown that the extent to which this primary ratio measurement method can deliver accurate results is still subject of active research. In this review, we will summarize the fundamental prerequisites behind isotope dilution mass spectrometry and discuss their practical limits of validity and effects on the accuracy of the obtained results. This review is not to be viewed as a critique of isotope dilution; rather its purpose is to highlight the lesser studied aspects that will ensure and elevate current supremacy of the results obtained from this method.

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Citations

Feb 12, 2009·Analytical and Bioanalytical Chemistry·Juris MeijaZoltán Mester
Jun 10, 2010·Analytical and Bioanalytical Chemistry·Jörg Bettmer
Aug 9, 2011·Analytical and Bioanalytical Chemistry·Claudia SwartDetlef Schiel
Sep 27, 2012·Analytical and Bioanalytical Chemistry·Claudia FrankDetlef Schiel
Oct 16, 2012·Analytical and Bioanalytical Chemistry·Ilia RodushkinDouglas C Baxter
May 11, 2013·Analytical and Bioanalytical Chemistry·Claudia Swart
Apr 27, 2010·The Analyst·Ana González-AntuñaJ Ignacio García Alonso
Aug 26, 2014·Analytical and Bioanalytical Chemistry·Enea Pagliano
Jun 12, 2010·Expert Review of Proteomics·Marcelo A O da SilvaMarco A Z Arruda
Aug 5, 2009·Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences·Michela TomaiuoloElvira Grandone
Oct 9, 2015·Analytical Chemistry·Enea PaglianoJuris Meija
Jan 18, 2011·Talanta·Claudia SwartDetlef Schiel
Jan 31, 2012·Talanta·Stéphanie ClémensThierry Guérin
Jan 29, 2009·The Analyst·Zeland Muccio, Glen P Jackson
May 22, 2009·Analytical Chemistry·Laurent OuerdaneJuris Meija
May 25, 2010·Analytical Chemistry·Diane Beauchemin
Jun 25, 2021·Analytical and Bioanalytical Chemistry·Enea Pagliano

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