Parafalcine and bilateral convexity neurosarcoidosis mimicking meningioma: case report and review of the literature

Neurosurgery
R J JacksonR L Harper

Abstract

Sarcoidosis is a granulomatous disorder of unknown origin that may rarely present solely as an intracranial tumor. Neurosarcoidosis can mimic more common disease processes, such as meningioma, glioma, or metastases. It is important to keep neurosarcoidosis in mind, both preoperatively and intraoperatively, to guide appropriate treatment. We present a case of neurosarcoidosis mimicking a parafalcine and bilateral convexity meningioma. A 44-year-old African-American woman was referred to our institution with a diagnosis of meningioma based on a 4-month history of headaches, decreased memory, personality changes, and decreased coordination and on the results of axial computed tomography, which revealed a parafalcine and bilateral convexity mass. Cerebral arteriography and magnetic resonance imaging were performed to better characterize the lesion for anticipated surgery. Despite corticosteroid therapy, the patient continued to have progressive symptoms and underwent surgery. Intraoperative frozen sections were consistent with neurosarcoidosis. The mass was then significantly debulked unilaterally. Laboratory studies and follow-up examinations revealed no evidence of systemic sarcoidosis. The patient received corticosteroid therapy...Continue Reading

References

Oct 1, 1992·Archives of Neurology·B J SternG Belendiuk
Apr 1, 1992·Journal of Neurology, Neurosurgery, and Psychiatry·D RanouxJ L Mas
Jun 1, 1991·Journal of Neurology, Neurosurgery, and Psychiatry·K T KhawF Schon
Aug 1, 1985·Neurology·V OksanenC Grönhagen-Riska
Oct 1, 1986·Surgical Neurology·R K OsenbachJ Gutierrez
Dec 1, 1985·Journal of Neurosurgery·W C ClarkJ H Robertson
Mar 1, 1981·Surgical Neurology·D W Cahill, M Salcman
Jul 1, 1995·Journal of Computer Assisted Tomography·D A FinelliY Takaoka
Apr 1, 1995·Acta Neurologica Scandinavica·U SchickM Schwarz
Sep 1, 1995·Archives of Neurology·B N AgboguG Yang
Mar 1, 1994·American Journal of Respiratory and Critical Care Medicine·A BellocqA J Hance
Oct 1, 1994·The Journal of Clinical Investigation·J D FormanD R Moller
Oct 1, 1993·The American Review of Respiratory Disease·D G KernJ C Varone
Apr 24, 1997·The New England Journal of Medicine·L S NewmanL A Maier
Dec 8, 1998·American Journal of Public Health·C S RoseK Kreiss
Jan 1, 1965·Archives of Neurology·A SILVERSTEINL E SILTZBACH
Jul 1, 1955·Journal of Neurosurgery·S A SKILLICORN, R W GARRITY

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Citations

May 17, 2001·Journal of Neurosurgery·A O DareW Grand
Aug 24, 2000·Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc·L B Strickland-MarmolA M Rojiani
Dec 3, 2009·The Clinical Neuropsychologist·Matias Mariani, Prathiba Shammi
Nov 24, 2007·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·C LiuC A Glaser
Nov 4, 2000·Journal of Neurosurgery·D A NowakC B Lumenta
Feb 24, 2001·Neurologia Medico-chirurgica·M UchinoH Mutou
Jul 6, 2000·European Radiology·D PickuthS H Heywang-Köbrunner
Jan 7, 2003·Human Pathology·Mahlon D JohnsonPaul L Moots

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