PMID: 8611199Mar 1, 1996Paper

Paraganglioma of the cauda equina. A case report and review of the literature

APMIS : Acta Pathologica, Microbiologica, Et Immunologica Scandinavica
J BakB Spännare

Abstract

A 59-year-old man presented with clinical evidence of a primary tumor of the cauda equina region. It was well circumscribed and was completely removed by neurosurgery. Routine staining showed that it had structural similarities to an ependymoma, but immunohistochemistry with antisera to synaptophysin, NSE, chromogranin-A and PGP 9.5 proved it to be a neuroendocrine tumor, i.e. a paraganglioma. We propose the use of endocrine markers in cases with tumors of the cauda equina to differentiate a paraganglioma from an ependymoma. Paragangliomas appear to have a better clinical outcome than ependymomas. Recurrence after surgery for a paraganglioma in the cauda equina region, especially if it is encapsulated, is rarely encountered.

References

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Citations

Mar 31, 2005·Journal of Neurosurgery. Spine·Miguel Gelabert-González
Jan 27, 2015·Korean Journal of Spine·Han San OhKwan Ho Park
Nov 16, 2010·Journal of Clinical Neurophysiology : Official Publication of the American Electroencephalographic Society·Jon P HobbsJohn M Beggs

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