PMID: 8953257Nov 1, 1996Paper

Parallel computation enables precise description of Ca2+ distribution in nerve terminals

Bulletin of Mathematical Biology
S AharonHanna Parnas

Abstract

Parallel computation employing a domain decomposition method was used to calculate precisely without approximations the spatio-temporal distribution of Ca2+ in nerve terminals. The results showed, contrary to expectations, that for equal admitted Ca2+ currents at low (one channel open) and high (four channels open) depolarization, the average Ca2+ concentration at the release area is higher at the low depolarization. These calculations provide additional support for the Ca(2+)-voltage hypothesis for neurotransmitter release.

References

Jan 1, 1990·International Review of Neurobiology·H ParnasL A Segel
May 1, 1986·Proceedings of the National Academy of Sciences of the United States of America·R S Zucker, A L Fogelson
Jan 1, 1987·Annual Review of Neuroscience·G J AugustineS J Smith
Oct 1, 1988·Trends in Neurosciences·R W TsienA P Fox
Oct 1, 1988·Trends in Neurosciences·S J Smith, G J Augustine
May 1, 1989·Biophysical Journal·H ParnasI Parnas
Oct 1, 1985·The Journal of Physiology·G J AugustineS J Smith
Feb 1, 1986·Pflügers Archiv : European journal of physiology·I ParnasJ Dudel
Jan 1, 1987·Canadian Journal of Physiology and Pharmacology·J M WojtowiczH L Atwood
Jun 1, 1980·The Journal of Physiology·N B Datyner, P W Gage
Dec 1, 1994·The Journal of Membrane Biology·H Parnas, I Parnas
Dec 1, 1993·Computer Methods and Programs in Biomedicine·S Aharon, M Bercovier

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.