Parallelization of microfluidic flow-focusing devices

Physical Review. E
E AmstadDavid A Weitz

Abstract

Microfluidic flow-focusing devices offer excellent control over fluid flow, enabling formation of drops with a narrow size distribution. However, the throughput of microfluidic flow-focusing devices is limited and scale-up through operation of multiple drop makers in parallel often compromises the robustness of their operation. We demonstrate that parallelization is facilitated if the outer phase is injected from the direction opposite to that of the inner phase, because the fluid injection flow rate, where the drop formation transitions from the squeezing into the dripping regime, is shifted towards higher values.

References

May 21, 2005·Physical Review Letters·Piotr GarsteckiGeorge M Whitesides
Jul 29, 2006·Lab on a Chip·Levent YobasNagarajan Ranganathan
Feb 1, 2008·Physical Review Letters·Benjamin DolletMichel Versluis
Sep 25, 2008·Lab on a Chip·C HoltzeD A Weitz
Jun 13, 2009·Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics·Katherine J HumphryDavid A Weitz
Oct 2, 2009·Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics·A R AbateD A Weitz
Feb 10, 2010·Proceedings of the National Academy of Sciences of the United States of America·Jeremy J AgrestiDavid A Weitz
Jul 10, 2010·Lab on a Chip·Volkert van SteijnMichiel T Kreutzer
Mar 10, 2012·Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics·Tomasz GlawdelCarolyn L Ren
Oct 13, 2015·Nature Biotechnology·Assaf RotemBradley E Bernstein

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Citations

Feb 15, 2020·Micromachines·Ying XuQuanjun Liu
Jun 9, 2019·Nature Communications·Piotr M KorczykPiotr Garstecki
Jan 24, 2018·Lab on a Chip·Armend G HåtiEsther Amstad
Sep 29, 2019·Lab on a Chip·M SolsonaM Odijk
Aug 11, 2018·Archives of Pharmacal Research·Bahman HomayunHyo-Jick Choi
Mar 27, 2021·Journal of Controlled Release : Official Journal of the Controlled Release Society·Alejandro ForiguaKatherine S Elvira

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