Parameters for monitoring treatment effects in CIDP with anti-MAG/SGPG IgM antibody

Muscle & Nerve
Y TagawaS Hosokawa

Abstract

We used cycles of plasma exchange and intravenous cyclophosphamide to treat a patient who had chronic inflammatory demyelinating polyneuropathy with anti-myelin-associated glycoprotein/sulfoglucuronylparagloboside IgM antibody. After treatment, serum anti-sulfoglucuronylparagloboside IgM antibody titers were reduced significantly, and clear symptomatic improvement followed. The percentage of CD57-positive lymphocytes and natural killer cell activity had also returned to normal. Our findings indicate that serial measurements of these parameters are useful for monitoring treatment effect in this disease.

Citations

May 18, 2016·The International Journal of Neuroscience·Giuliana GalassiFranco Valzania
Nov 2, 2016·The Cochrane Database of Systematic Reviews·Michael Pt Lunn, Eduardo Nobile-Orazio

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