Parametric level set reconstruction methods for hyperspectral diffuse optical tomography.

Biomedical Optics Express
Fridrik LarussonEric L Miller

Abstract

A parametric level set method (PaLS) is implemented for image reconstruction for hyperspectral diffuse optical tomography (DOT). Chromophore concentrations and diffusion amplitude are recovered using a linearized Born approximation model and employing data from over 100 wavelengths. The images to be recovered are taken to be piecewise constant and a newly introduced, shape-based model is used as the foundation for reconstruction. The PaLS method significantly reduces the number of unknowns relative to more traditional level-set reconstruction methods and has been show to be particularly well suited for ill-posed inverse problems such as the one of interest here. We report on reconstructions for multiple chromophores from simulated and experimental data where the PaLS method provides a more accurate estimation of chromophore concentrations compared to a pixel-based method.

References

May 24, 1994·Proceedings of the National Academy of Sciences of the United States of America·D A BoasA G Yodh
Jun 29, 1997·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·E GrattonM Fabiani
Dec 10, 1999·Physics in Medicine and Biology·M Schweiger, S R Arridge
Sep 12, 2002·Physics in Medicine and Biology·T DurduranA G Yodh
Apr 1, 2003·Photochemical & Photobiological Sciences : Official Journal of the European Photochemistry Association and the European Society for Photobiology·Paola TaroniRinaldo Cubeddu
Sep 30, 2003·Proceedings of the National Academy of Sciences of the United States of America·Subhadra SrinivasanKeith D Paulsen
Jun 3, 2005·Physics in Medicine and Biology·Murat GuvenBritton Chance
Sep 22, 2005·Technology in Cancer Research & Treatment·Sergio FantiniNing Liu
May 30, 2006·Proceedings of the National Academy of Sciences of the United States of America·Ben BrooksbyKeith D Paulsen
Mar 16, 2007·Proceedings of the National Academy of Sciences of the United States of America·Albert CerussiBruce J Tromberg
Aug 1, 2007·Physics in Medicine and Biology·Gregory BovermanDavid A Boas
Feb 6, 2008·IEEE Transactions on Image Processing : a Publication of the IEEE Signal Processing Society·T F Chan, L A Vese
Mar 6, 2008·Applied Optics·B W PogueK D Paulsen
Jan 31, 2000·Optics Express·M A FranceschiniS Fantini
Jul 2, 2009·Journal of Biomedical Optics·Bernhard Brendel, Tim Nielsen
Apr 22, 2010·Clinical Cancer Research : an Official Journal of the American Association for Cancer Research·Hany SolimanGregory J Czarnota
Apr 13, 2011·Biomedical Optics Express·Fridrik LarussonEric L Miller

❮ Previous
Next ❯

Citations

Feb 24, 2015·IEEE Transactions on Bio-medical Engineering·Yu AnJie Tian
Feb 16, 2013·Biomedical Optics Express·Fridrik LarussonEric L Miller
Sep 28, 2017·IEEE Transactions on Medical Imaging·Dong LiuJiangfeng Du

❮ Previous
Next ❯

Software Mentioned

Matlab
like
DOT
PaLS

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.