Parametric regression on cumulative incidence function

Biostatistics
Jong-Hyeon Jeong, Jason P Fine

Abstract

We propose parametric regression analysis of cumulative incidence function with competing risks data. A simple form of Gompertz distribution is used for the improper baseline subdistribution of the event of interest. Maximum likelihood inferences on regression parameters and associated cumulative incidence function are developed for parametric models, including a flexible generalized odds rate model. Estimation of the long-term proportion of patients with cause-specific events is straightforward in the parametric setting. Simple goodness-of-fit tests are discussed for evaluating a fixed odds rate assumption. The parametric regression methods are compared with an existing semiparametric regression analysis on a breast cancer data set where the cumulative incidence of recurrence is of interest. The results demonstrate that the likelihood-based parametric analyses for the cumulative incidence function are a practically useful alternative to the semiparametric analyses.

References

Apr 1, 1992·Statistics in Medicine·E L Korn, F J Dorey
Jan 16, 1999·Journal of the National Cancer Institute·T G KarrisonP Meier
Mar 23, 2004·Biometrics·John Bryant, James J Dignam

❮ Previous
Next ❯

Citations

Jan 20, 2012·The New England Journal of Medicine·Margaret L GourlayUNKNOWN Study of Osteoporotic Fractures Research Group
Jan 28, 2012·Clinical Cancer Research : an Official Journal of the American Association for Cancer Research·James J DignamMasha Kocherginsky
Oct 23, 2010·BMC Medical Research Methodology·Hyun J LimNathaniel Osgood
Nov 15, 2011·Theoretical Biology & Medical Modelling·Zahra ShayanNajaf Zare
Jan 30, 2016·American Journal of Preventive Medicine·Margaret L GourlayUNKNOWN Osteoporotic Fractures in Men (MrOS) Research Group
Oct 24, 2012·Biometrical Journal. Biometrische Zeitschrift·Haiwen ShiJong-Hyeon Jeong
Aug 26, 2010·Cancer·Loren K MellSteven J Chmura
Oct 29, 2014·Menopause : the Journal of the North American Menopause Society·Margaret Lee GourlayUNKNOWN Women’s Health Initiative Investigators
Jan 13, 2015·Biology of Blood and Marrow Transplantation : Journal of the American Society for Blood and Marrow Transplantation·Aaron C LoganUNKNOWN Center for International Blood and Marrow Transplantation
Jun 28, 2014·International Journal of Radiation Oncology, Biology, Physics·Ruben CarmonaLoren K Mell
Dec 23, 2016·Statistics in Medicine·Paul C LambertMichael J Crowther
Jul 3, 2013·Medical Decision Making : an International Journal of the Society for Medical Decision Making·Serge M A SomdaThomas Filleron
Aug 20, 2008·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·James J Dignam, Maria N Kocherginsky
Aug 18, 2010·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Loren K Mell, Jong-Hyeon Jeong
Jul 16, 2010·Waste Management & Research : the Journal of the International Solid Wastes and Public Cleansing Association, ISWA·Ester GutiérrezPilar González-Torre
Jan 11, 2011·Statistical Methods in Medical Research·Giorgos Bakoyannis, Giota Touloumi
Jun 14, 2017·Statistics in Medicine·Giorgos BakoyannisConstantin T Yiannoutsos
Jun 27, 2015·Statistical Methods in Medical Research·Jeong Youn Lim, Jong-Hyeon Jeong
Jan 29, 2019·Clinical and Experimental Nephrology·Keita HiranoAkira Hishida
Feb 28, 2017·Journal of the Royal Statistical Society. Series B, Statistical Methodology·Lu Mao, D Y Lin
Feb 25, 2017·Statistics in Medicine·M RowleyA C C Coolen

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.