PMID: 9525839Apr 3, 1998Paper

Paraneoplastic limbic encephalitis with immature ovarian teratoma--a case report

Journal of Neuro-oncology
A AydinerI Baral

Abstract

Paraneoplastic limbic encephalitis (PLE) is a remote, nonmetastatic complication of carcinoma. Neuropsychiatric symptoms usually predate the diagnosis of cancer by 3 months to 6 years and very rarely the symptoms develop after the diagnosis of malignancy. We report the first case of limbic encephalitis associated with an immature ovarian teratoma. Within the month following the diagnosis of the tumor with pathologic stage Ia, somewhat acutely she developed neuropsychiatric symptoms that was exclusively a limbic disorder with impairments in almost every realm of limbic function. This case may show us that it is important to recognize the neuropsychiatric symptoms of PLE as the first manifestation of a very small malignant ovarian tumor and to aggressively try to identify the underlying cancer.

Citations

Dec 31, 1998·Current Opinion in Neurology·J Rees
Jun 5, 2004·Journal of Neuro-ophthalmology : the Official Journal of the North American Neuro-Ophthalmology Society·Rajeev H MuniAgnes M F Wong
Nov 2, 2004·Obstetrics and Gynecology·Michael H BlochSetsuko K Chambers
Feb 22, 2005·Pediatric Radiology·Rebecca Stein-WexlerJames A Brunberg
Sep 24, 2005·Annals of Neurology·Roberta VitalianiJosep Dalmau
Apr 14, 2007·Journal of Neuro-oncology·Yasuyo TonomuraSatoshi Ueno
Nov 24, 1999·The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques·R B TaylorR Wennberg
Jan 1, 2012·Clinics and Practice·Sofia MarkoulaAthanassios P Kyritsis

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