Parasellar T2 dark sign on MR imaging in patients with lymphocytic hypophysitis.

AJNR. American Journal of Neuroradiology
Y NakataK Ohtomo

Abstract

MR imaging findings of LYH and pituitary adenomas are similar, but the therapeutic strategies are completely different. The purpose of this study was to evaluate sellar and parasellar MR imaging findings in patients with both diseases, as well as characteristic clinical findings. Clinical findings, including endocrinologic study and MR images of 20 patients with LYH and 22 patients with pituitary adenoma, were retrospectively reviewed. We evaluated the MR images in relation to the following: 1) the PPHI on T1-weighted images, 2) thickened stalk (>3.5 mm), 3) pituitary symmetry, 4) pituitary enhancement pattern, 5) a dural tail, and 6) parasellar signal intensity on T2- and T1-weighted images. Between patients with LYH and those with pituitary adenoma, a significant difference was identified for the number of patients with loss of PPHI, thickened stalk, pituitary symmetry, homogeneous enhancement, and parasellar dark signal intensity on T2-weighted images by statistical analysis (Fisher exact probability test, P < .05). Among them, only parasellar dark signal intensity on T2-weighted images had no false-positive cases. The parasellar T2 dark sign can be a specific finding used to distinguish pituitary adenoma from LYH.

References

Sep 1, 1991·Radiographics : a Review Publication of the Radiological Society of North America, Inc·D E JohnsenL L Coleman
May 1, 1991·Journal of Computer Assisted Tomography·N SatoK Tomioka
Feb 1, 1988·The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques·M W McDermottE Wilkins
Dec 1, 1986·Radiology·W KucharczykT H Newton
Mar 1, 1987·Journal of Computer Assisted Tomography·I FujisawaY Nakano
Jun 13, 1985·The New England Journal of Medicine·A L BarkanJ C Marshall
Sep 2, 1993·The New England Journal of Medicine·H ImuraH Yamabe
Aug 1, 1996·Endocrine Journal·T IshiharaN Hattori
May 23, 1998·Neuroradiology·S SaiwaiT Miyamoto
Oct 28, 1998·Endocrine Journal·H M HeshmatiG Turpin
Nov 12, 1998·Acta neurochirurgica·T IuchiA Yamaura
Jul 21, 2000·Australasian Radiology·D A LeggettR J Anderson
Apr 21, 2001·Journal of Endocrinological Investigation·M Durán MartínezS Monereo Megías
Jun 1, 2001·Journal of Endocrinological Investigation·Y NakamuraH Koshiyama
Nov 28, 2001·Journal of Neurology, Neurosurgery, and Psychiatry·N TubridyR Howard
Jan 25, 2002·Acta neurochirurgica·D E H FlanaganP D Lees
Oct 18, 2002·Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia·Anita SkandarajahAndrew H Kaye
Oct 31, 2003·European Journal of Endocrinology·Antonio BellastellaAnnamaria De Bellis
Nov 18, 2003·Journal of Neurology, Neurosurgery, and Psychiatry·A LecubeR Simó
Jul 17, 2004·Endocrine Journal·Seong Jin LeeMoon Gi Choi
Aug 18, 2004·Journal of Neurosurgery·Gilberto K K LeungEdward R Laws
Jan 1, 2005·European Radiology·Jean-François BonnevilleFrançoise Cattin
Jan 7, 2005·Endocrine Reviews·Patrizio CaturegliNoel R Rose
Oct 21, 2005·Acta neurochirurgica·A Pérez-NúñezR D Lobato
Apr 26, 2008·Endocrine Reviews·Stephanie T PageWilliam J Bremner
Jul 8, 2008·Journal of Neuro-oncology·Hui WangYing Guo
Jul 25, 2009·AJNR. American Journal of Neuroradiology·A GutenbergP Caturegli

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Citations

Mar 20, 2012·Endocrine·A Glezer, M D Bronstein
Oct 1, 2014·Pediatric Neurology·Joaquin A PenaTimothy E Lotze
Aug 19, 2015·Neuropathology : Official Journal of the Japanese Society of Neuropathology·Rie SaitoAkiyoshi Kakita
Nov 20, 2012·Seminars in Roentgenology·Anna DermanGirish M Fatterpekar
Oct 16, 2012·Clinical Radiology·A M MortimerS A Renowden
Oct 9, 2012·Neurosurgery Clinics of North America·Christopher P Hess, William P Dillon
Jan 7, 2016·Journal of Postgraduate Medicine·S SankheS Khare
Apr 21, 2012·Annales d'endocrinologie·Jean-François Bonneville
Jan 1, 2014·Pituitary·Shruti KhareNalini S Shah
Jun 30, 2016·Hormone Research in Pædiatrics·Allison J PollockDavid B Allen
Apr 1, 2017·Neurosurgery·Carlos Zamora, Mauricio Castillo
Aug 9, 2020·AJNR. American Journal of Neuroradiology·R KurokawaO Abe
Aug 22, 2018·Acta neurologica Belgica·Alessandro CaporlinguaAntonio Santoro
May 13, 2018·Pituitary·Tommaso TartaglioneLaura De Marinis
Jun 22, 2021·Clinical Imaging·Andrei Jipa, Vikas Jain
Sep 2, 2021·ENeurologicalSci·Yuki UrushidaMikio Shoji

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