Parathormone response to thyroid surgery

American Journal of Surgery
Ronan A CahillR Gordon K Watson

Abstract

Confident determination of adequate residual parathyroid function early after thyroid surgery could facilitate the discharge of patients soon after their operation without the need for subsequent serum calcium monitoring and/or calcium and vitamin D supplementation. Thirty-one patients who underwent 33 thyroid operations (22 unilateral lobectomies and 11 bilateral thyroid resections) were prospectively studied. Parathormone (PTH) levels were measured intraoperatively, and serum calcium was monitored before and after surgery to determine PTH and calcium homeostatic response to thyroid surgery. A significant decrease in circulating PTH occurred during 27 procedures, most markedly after specimen mobilization. Intraoperative PTH and postoperative calcium levels were lowest in those who underwent bilateral operations. Patients who underwent unilateral procedures experienced significant decreases in PTH but not postoperative calcium levels. A PTH level >50% of baseline predicted normocalcemia by postoperative day 3. However, PTH level did not accurately triage other patients' risk for postoperative hypocalcemia. A decrease in PTH levels intraoperatively is a common event during both unilateral and bilateral thyroid operations. Althou...Continue Reading

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Citations

Apr 29, 2008·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·Ottavio CavicchiAlberto Rinaldi Ceroni
Dec 15, 2010·World Journal of Surgery·James Kirkby-BottFausto Palazzo
May 10, 2008·American Journal of Surgery·Antonio ToniatoPaola Sartori
Jan 5, 2011·Clinical Otolaryngology : Official Journal of ENT-UK ; Official Journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery·E M QuinnH P Redmond
Jul 23, 2015·Archives of Endocrinology and Metabolism·Karen Manoela RosaVergilius José Furtado de Araújo Filho

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