PMID: 1115471Mar 1, 1975Paper

Parathyroid function in patients with pheochromocytoma

Annals of Internal Medicine
S S MillerG M Tyce

Abstract

Serum calcium, serum immunoreactive parathyroid hormone (PTH), and plasma immunoreactive calcitonin were measured in 12 patients with catecholamine-secreting tumors. Only two patients had high serum calcium and immunoreactive PTH concentrations (one also had high basal immunoreactive calcitonin); in both, the hypercalcemia persisted after removal of their pheochromocytomas but was corrected by removal of hyperplastic parathyroid glands and medullary thyroid carcinomas. Of the 10 patients with normal serum calcium and immunoreactive PTH concentrations, 2 had high immunoreactive calcitonin concentrations and medullary thyroid carcinomas alone were found. Our results suggest that [1] hypercalcemia occurs infrequently in patients with pheochromocytoma, [2] chronic circulating catecholamine excess does not cause increased immunoreactive PTH or immunoreactive calcitonin secretion in patients with pheochromocytoma, and [3] the parathyroid disease in patients with pheochromocytoma is a genetically determined component of multiple endocrine neoplasia.

Citations

Dec 1, 1988·Disease-a-month : DM·J P Bilezikian
Aug 1, 1979·European Journal of Obstetrics, Gynecology, and Reproductive Biology·S SukenikJ Stern
Aug 12, 1982·The New England Journal of Medicine·S J MarxG D Aurbach
Sep 1, 1976·Postgraduate Medical Journal·R R GhoseJ S Woodhead
Jul 1, 1981·Postgraduate Medical Journal·B J Fairhurst, S P Shettar
May 1, 1978·The Journal of Clinical Investigation·J W BlumA Guillebeau
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Jan 1, 1980·International Journal of Health Services : Planning, Administration, Evaluation·H S Berliner, J W Salmon
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Jan 1, 1979·Endocrine Research Communications·P R MarquesC C Gale
Jun 1, 1997·Current Problems in Surgery·F K ChanJ P Bilezikian

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