PMID: 9442359Jan 27, 1998Paper

Parathyroid hormone-related peptide--a smooth muscle tone and proliferation regulatory protein

Current Opinion in Nephrology and Hypertension
T MassfelderJ J Helwig

Abstract

Parathyroid hormone-related protein (PTHrP) appears to play crucial roles in the cardiovascular system. Over the past few years it has become apparent that there is more than one receptor recognizing parathyroid hormone or PTHrP, or both, and that PTHrP is not only a potent vasodilator of vascular smooth muscle cell tone, but is also a regulator of vascular smooth muscle cell proliferation and a secretagogue of renin and vasopressin. Investigators in several laboratories have started to query whether PTHrP intervenes in vascular diseases such as hypertension, (re)stenosis-atherosclerosis and endotoxaemia.

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Citations

Oct 18, 2000·Endocrinology and Metabolism Clinics of North America·G J Strewler
Jan 25, 2014·Scandinavian Journal of Clinical and Laboratory Investigation·Anders NordholmEwa Lewin
Mar 24, 2005·Journal of Cellular Biochemistry·James F Whitfield
Jul 26, 2013·American Journal of Physiology. Cell Physiology·John S Torday
Mar 22, 2001·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·T MassfelderJ J Helwig
May 16, 2019·British Journal of Pharmacology·T John Martin, Rachelle W Johnson

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