Paratuberculosis in dairy cattle: variation of the antibody response in offspring attributable to the dam

Journal of Dairy Science
S S NielsenJ F Agger

Abstract

The objective of this study was to examine transmission of paratuberculosis in dairy cattle attributable to the dam. Milk samples were collected from 8131 cows in 110 Danish dairy herds. The level of antibodies to Mycobacterium avium subspecies paratuberculosis was determined by use of an ELISA. Information on dam and sire was obtained from the Danish Cattle database. The following two data sets were analyzed: Data set A contained all cows < or = 400 days in milk (n = 7410); data set B contained 1056 dam-daughter pairs present simultaneously in herds at the day of sampling. Cows > 400 days in milk were excluded. Linear mixed models were used to obtain variance components for the effect of sire in data set A and the effect of sire and dam-daughter pairs in data set B. Models for both data sets A and B included information previously shown to confound antibody level and information of the relative prevalence of paratuberculosis in the herd. In data set A, the effect explained by sire was 1.9%, whereas it was 6.3% in data set B. The effect from dam-daughter pairs was 7.7%. Those effects were all significant. It was concluded that the parental contribution was significant, and both heritability of susceptibility and vertical transm...Continue Reading

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Citations

Jun 3, 2009·Journal of Applied Microbiology·M M EltholthF J Guitian
May 11, 2010·Journal of Veterinary Diagnostic Investigation : Official Publication of the American Association of Veterinary Laboratory Diagnosticians, Inc·Solis NortonCord Heuer
Jan 8, 2008·The Journal of Veterinary Medical Science·Sota KobayashiAkiko Nishiguchi
Aug 27, 2005·Journal of the American Veterinary Medical Association·Sharif S Aly, Mark C Thurmond
Sep 27, 2005·Critical Reviews in Food Science and Nutrition·Tilak R DhimanAmy L Ure
Jun 4, 2008·American Journal of Veterinary Research·Munashe ChigerweJohn R Middleton
Jan 11, 2011·Comparative Immunology, Microbiology and Infectious Diseases·Auriol C PurdieRichard J Whittington

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