Parenchyma-sparing liver resection for hepatocellular carcinoma in left lateral section is associated with better liver volume recovery

HPB : the Official Journal of the International Hepato Pancreato Biliary Association
Kosuke KobayashiNorihiro Kokudo

Abstract

Left lateral sectionectomy (LLS) is frequently performed for surgical treatment of hepatocellular carcinoma (HCC) located in the left lateral section. However, no reports have described liver resection for such HCCs using a parenchyma-sparing strategy involving anatomic resection (AR) of segment II (S2 AR) or segment III (S3 AR). From 1994 to 2014, patients who underwent LLS and S2 AR or S3 AR for HCC were included in the analysis. Short- and long-term outcomes and pre- and postoperative LV were assessed. Of the 89 patients selected, 49 underwent LLS (LLS group) and 40 underwent S2 AR and S3 AR (S2/S3 AR group). The postoperative LV was not significantly smaller than the preoperative LV in the S2/S3 AR group (p = 0.114), whereas the postoperative LV was significantly smaller in the LLS group (p = 0.019). The overall survival (OS) and recurrence free survival (RFS) rates were not significantly different between the groups (OS, p = 0.056; RFS, p = 0.102). Parenchyma-sparing liver resection for HCC in the left lateral section is associated with better postoperative LV recovery than LLS with similar oncological outcomes. S2/S3 AR can be a reasonable therapeutic option when LLS results in the removal of more parenchyma than necessary.

References

Jul 1, 1993·Seminars in Surgical Oncology·M MakuuchiS Kawasaki
Jul 26, 2005·Annals of Surgery·Kiyoshi HasegawaMasatoshi Makuuchi
Jan 26, 2007·Annals of Surgical Oncology·Toshifumi WakaiKatsuyoshi Hatakeyama
Nov 17, 2009·Annals of Surgery·Joseph F BuellUNKNOWN World Consensus Conference on Laparoscopic Surgery
Sep 5, 2014·Annals of Surgery·Yoshihiro MiseNorihiro Kokudo

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Citations

Jul 19, 2020·Nature Reviews. Gastroenterology & Hepatology·Henrik PetrowskyPierre-Alain Clavien
Nov 15, 2020·HPB : the Official Journal of the International Hepato Pancreato Biliary Association·Hui LiHong Wu
Jul 28, 2021·HPB : the Official Journal of the International Hepato Pancreato Biliary Association·Genki WatanabeKiyoshi Hasegawa

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