Parent and public interest in whole-genome sequencing

Public Health Genomics
Daniel S DodsonBeth A Tarini

Abstract

The aim of this study was to assess the baseline interest of the public in whole-genome sequencing (WGS) for oneself, parents' interest in WGS for their youngest children, and factors associated with such interest. A random sample of adults from a probability-based nationally representative online panel was surveyed. All participants were provided basic information about WGS and then asked about their interest in WGS for themselves. Those participants who were parents were additionally asked about their interest in WGS for their children. The order in which parents were asked about their interest in WGS for themselves and for their child was randomized. The relationship between parent/child characteristics and interest in WGS was examined. The overall response rate was 62% (55% among parents). 58.6% of the total population (parents and nonparents) was interested in WGS for themselves. Similarly, 61.8% of the parents were interested in WGS for themselves and 57.8% were interested in WGS for their youngest children. Of note, 84.7% of the parents showed an identical interest level in WGS for themselves and their youngest children. Mothers as a group and parents whose youngest children had ≥2 health conditions had significantly mor...Continue Reading

Citations

Jun 3, 2016·Genetics in Medicine : Official Journal of the American College of Medical Genetics·Deborah A MarshallKathryn A Phillips
Mar 18, 2017·Genetic Testing and Molecular Biomarkers·Davit ChokoshviliPascal Borry
Mar 24, 2017·PloS One·Christopher H Wade, Kailyn R Elliott
Apr 15, 2018·Human Genomics·Taketoshi OkitaKazuto Kato
Aug 5, 2017·Genetics in Medicine : Official Journal of the American College of Medical Genetics·Megan A LewisDonald B Bailey
Apr 6, 2020·Journal of Community Genetics·Antti SaastamoinenPirjo Isohanni
Jun 27, 2020·Personalized Medicine·Holly EtchegaryDaryl Pullman
Nov 21, 2017·Translational Science of Rare Diseases·Janine LewisHenrietta Hyatt-Knorr
Nov 9, 2018·Journal of Community Genetics·Erin LePoireDeborah J Bowen
Jan 27, 2021·Journal of Human Genetics·Midori YamamotoAkira Hata
Mar 9, 2021·Social Science & Medicine·Simone ZhangDalton Conley

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