Parental bipolar disorder, family environment, and offspring psychiatric disorders: A systematic review.

Journal of Affective Disorders
Emma K StappHolly C Wilcox

Abstract

Our objective was to systematically review non-experimental studies of parental bipolar disorder (BD), current family environment, and offspring psychiatric disorders to identify characteristics of family environment associated with parental BD and risk for offspring psychiatric disorders. CINAHL, Embase, PsycINFO, and PubMed were searched using MeSH terms to identify studies on offspring of BD parents published through September 2017. We followed PRISMA guidelines and used the Risk of Bias Assessment Tool for Nonrandomized Studies (RoBANS). We calculated prevalence ratios and 95% confidence intervals to compare offspring psychiatric disorders within and across studies. Of 10,454 unique documents retrieved, we included 13 studies. The most consistent finding was lower parent-reported cohesion in families with a BD parent versus no parental psychiatric disorders. Family environment did not differ between BD parents and parents with other disorders. Offspring of BD parents had higher prevalence of psychiatric disorders than offspring of parents without psychiatric disorders but did not differ from offspring of parents with other disorders. Families with a BD child had higher conflict than families without a BD child. Comparisons ...Continue Reading

Citations

Aug 11, 2020·Perspectives in Psychiatric Care·Brayden N Kameg, Kirstyn M Kameg
Apr 16, 2021·European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology·Norma VerdoliniMiguel Bernardo

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Bipolar disorder is characterized by manic and/or depressive episodes and associated with uncommon shifts in mood, activity levels, and energy. Discover the latest research this illness here.

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