Parental calculation of pediatric paracetamol dose: a randomized trial comparing the Parental Analgesia Slide with product information leaflets

Paediatric Anaesthesia
Richard HixsonMika Hamilton

Abstract

To compare the ability of parents to calculate and demonstrate the correct paracetamol (acetaminophen) dose, interval, and frequency for their child when using either product information leaflets or the Parental Analgesia Slide. Prescribing information provided with over-the-counter medication may be a source of confusion for parents delivering analgesics to children at home. Accurate administration is essential to ensure safe and effective treatment of children's pain or fever. The Parental Analgesia Slide is a new device developed with the objective of improving parental dosing accuracy. In this prospective, randomized study, 160 parents accompanying children aged between one and 13 years old were randomly allocated to complete a paracetamol dose calculation and administration questionnaire using one of two sources of prescribing information. Absolute percentage dose error and the number of correct dosage intervals, frequencies, and demonstrated drug volumes were compared. Use of the Parental Analgesia Slide resulted in a reduction in the absolute percentage dose error from a median of 33.3 to 0% (P < 0.001) and an increase in the number of correct dosage intervals and frequencies (59/80 to 70/80, P = 0.046). There was no dif...Continue Reading

References

Jul 1, 1997·Archives of Pediatrics & Adolescent Medicine·H K Simon, D A Weinkle
Feb 21, 1998·The Journal of Pediatrics·J E HeubiH J Zimmerman
Jan 1, 2000·The Medical Journal of Australia·F K MilesE V O'Loughlin
Jan 4, 2001·Pediatric Emergency Care·S F LiE F Crain
Mar 13, 2001·The Journal of Laryngology and Otology·J J HomerP Semple
Jan 5, 2002·European Journal of Clinical Pharmacology·B J AndersonN H Holford
Nov 5, 2002·International Journal of Medical Informatics·Vimla L PatelJose F Arocha
Nov 29, 2002·Archives of Disease in Childhood·A Clarkson, I Choonara
Feb 4, 2003·Paediatric Anaesthesia·Päivi KankkunenPirjo Halonen
Feb 6, 2004·Pediatric Emergency Care·Ran D Goldman, Dennis Scolnik
Dec 6, 2006·Pain Management Nursing : Official Journal of the American Society of Pain Management Nurses·Margaret E Wilson, Helga L Helgadóttir
Dec 7, 2007·The Annals of Pharmacotherapy·Parisa SobhaniRobin L Corelli
Nov 4, 2008·Archives of Disease in Childhood·R HixsonF Holton
Jun 12, 2009·Clinical Toxicology : the Official Journal of the American Academy of Clinical Toxicology and European Association of Poisons Centres and Clinical Toxicologists·Leah TzimenatosUNKNOWN Pediatric Therapeutic Error Study Group

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Citations

Jul 25, 2013·Journal of Community Health Nursing·Colleen AndersonAndrea Brennan-Hunter
Mar 17, 2015·Expert Opinion on Drug Safety·José Joaquín MiraVirtudes Pérez-Jover
Nov 3, 2012·Pediatric Clinics of North America·Daniel R Neuspiel, Erin H Stubbs
Apr 27, 2011·Paediatric Anaesthesia·Alan F Merry, Brian J Anderson
Jan 1, 2013·Health Services Insights·Daniel R Neuspiel, Melissa M Taylor

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