Parental Characteristics Associated With Outcomes in Youth With Type 2 Diabetes: Results From the TODAY Clinical Trial

Diabetes Care
Ruth S WeinstockPatrice M Yasuda

Abstract

This study examined parental factors associated with outcomes of youth in the Treatment Options for type 2 Diabetes in Adolescents and Youth (TODAY) clinical trial. Of 699 youth with type 2 diabetes in the TODAY cohort, 623 (89.1%) had a parent participate and provide data at baseline, including weight, HbA1c, blood pressure, symptoms of depression, binge eating (BE), and medical history. Youth were followed 2-6.5 years. Data were analyzed using regression models and survival curve methods. Parental diabetes (43.6% of parents) was associated with higher baseline HbA1c (P < 0.0001) and failure of youths to maintain glycemic control on study treatment (53.6% vs. 38.2% failure rate among those without a diabetic parent, P = 0.0002). Parental hypertension (40.6% of parents) was associated with hypertension in youth during TODAY (40.4% vs. 27.4% of youth with and without parental hypertension had hypertension, P = 0.0008) and with higher youth baseline BMI z scores (P = 0.0038). Parents had a mean baseline BMI of 33.6 kg/m(2). Parental obesity (BMI >30 kg/m(2)) was associated with higher baseline BMI z scores in the youth (P < 0.0001). Depressive symptoms in parents (20.6% of parents) were related to youth depressive symptoms at bas...Continue Reading

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Citations

Apr 6, 2017·Pediatric Diabetes·Andrea KriskaUNKNOWN TODAY Study Group
Jun 9, 2017·The Journal of Cardiovascular Nursing·EunSeok ChaMelissa Spezia Faulkner
Jul 13, 2018·Pediatric Diabetes·Phillip ZeitlerDavid M Maahs
Nov 7, 2019·Psychology, Health & Medicine·Lauren B ShomakerJack A Yanovski
Aug 29, 2020·Current Diabetes Reports·Lauren D Gulley, Lauren B Shomaker
May 7, 2021·Iranian Journal of Nursing and Midwifery Research·Mahnaz SanjariNeda Mehrdad
Nov 23, 2021·World Journal of Pediatrics : WJP·Majidreza AkbarizadehFereshteh Ghaljaei

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