Parental decisions regarding a prenatally detected fetal chromosomal abnormality and the impact of genetic counseling: an analysis of 38 cases with aneuploidy in Southeast Turkey.

Journal of Genetic Counseling
Mahmut BalkanTurgay Budak

Abstract

This study investigated parental decision-making to terminate or continue a pregnancy after prenatal diagnosis of a chromosomal abnormality among a sample of patients in Southeast Turkey. Between 2004 and 2007, 1068 amniocentesis tests were performed in the Medical Biology and Genetic Department Laboratory at Dicle University. Aneuploidy was found in 38 cases (3.56%). Genetic counseling was provided for the couples that received abnormal results, and they were later interviewed and asked if they had continued or interrupted the pregnancy after the diagnosis. When confronted with autosomal aneuploidy in which a severe prognosis was expected, 85% of cases decided to terminate the pregnancy. When confronted with sex chromosome aneuploidy with a low risk of an abnormal clinical phenotype 60% of cases decided to continue the pregnancy. Among the diagnoses with aneuploidy, pregnancy was continued in 21.1% of cases due to religious beliefs regardless of whether there was a low or severe risk of an abnormal clinical phenotype. These findings indicate that both severity of abnormality and religiosity play an important role in genetic counseling patients' decision-making processes and outcomes in Turkey. In addition, the findings suggest...Continue Reading

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Citations

Sep 25, 2012·Journal of Genetic Counseling·Anne HawkinsLouanne Hudgins
Oct 8, 2011·Genetic Testing and Molecular Biomarkers·Esra AtamanFerda Ozkinay
Mar 19, 2014·International Journal of Nursing Studies·Kimberly A Allen
Jul 20, 2012·Best Practice & Research. Clinical Obstetrics & Gynaecology·Eugene Pergament, Deborah Pergament
Jul 31, 2012·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Tze Kin LauRitsuko K Pooh
Jan 13, 2012·Genetics in Medicine : Official Journal of the American College of Medical Genetics·Kwon Chan JeonPatricia Goodson
Feb 3, 2018·Health Expectations : an International Journal of Public Participation in Health Care and Health Policy·Robyn LottoNatalie Armstrong
Jan 26, 2018·Journal of Genetic Counseling·Jessica LuBeatrice A Chen
Mar 17, 2010·Journal of Genetic Counseling·Cassandra L Perry, Martha J Henry
Aug 4, 2018·Genetics in Medicine : Official Journal of the American College of Medical Genetics·Adrina ZhongHelen Dimaras
May 29, 2020·Omega·Valerie FlemingClaudia Meier-Magistretti
Mar 9, 2018·Journal of Reproductive and Infant Psychology·Rita LuzRachel Vieux
Oct 6, 2020·Frontiers in Pediatrics·DonnaMaria E CortezzoAmy Schlegel
Dec 31, 2016·Journal of Genetic Counseling·Amy R Reed, Kathryn L Berrier
Nov 4, 2021·The Journal of Obstetrics and Gynaecology Research·Nobuhiro Suzumori

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