Parental Reports of Prodromal Psychopathology in Pediatric Bipolar Disorder

Current Neuropharmacology
Mariely HernandezGianni L Faedda

Abstract

Early psychopathology in children diagnosed with Bipolar Disorder (BD) remains poorly characterized. Parental retrospective reports provide helpful details on the earliest manifestations and their evolution over time. These symptoms occur early in the course of BD, often before a formal diagnosis is made and/or treatment is implemented, and are of great importance to early recognition and prevention. Parents of pre-pubertal children and adolescents with DSM-IV diagnoses of BD attending an outpatient mood disorders clinic provided retrospective ratings of 37 symptoms of child psychopathology. Stability and comorbidity of diagnoses were evaluated, and severity of symptoms for each subject was assessed by identifying the earliest occurrence of the reported symptoms causing impairment. Severe mood instability, temper tantrums, anxiety symptoms, sleep disturbances and aggression were among the most common signs of psychopathology reported in children diagnosed with BD before puberty. Symptoms were already apparent in the first three years in 28%, and formal diagnoses were made before the age of 8 y in the majority of cases. Retrospective parental reports of early symptoms of psychopathology in pre-pubertal children with BD revealed ...Continue Reading

Citations

Jun 13, 2019·Journal of Psychosocial Nursing and Mental Health Services·Ann Roselle
Jan 6, 2018·Harvard Review of Psychiatry·Ciro MarangoniRoss J Baldessarini
Feb 23, 2020·Journal of Child and Adolescent Psychopharmacology·Gonzalo Salazar de PabloChristoph U Correll
Oct 4, 2018·Journal of Abnormal Child Psychology·Juan J Madrid-ValeroS Alexandra Burt
Jun 25, 2021·The World Journal of Biological Psychiatry : the Official Journal of the World Federation of Societies of Biological Psychiatry·Alessio SimonettiGabriele Sani
Aug 10, 2021·Frontiers in Psychiatry·Alessio SimonettiKirti Saxena
Aug 11, 2021·Journal of Affective Disorders·Tong GuoYu-Tao Xiang
Nov 2, 2020·Neuropsychobiology·Natalia ZverevaLuydmila Pyatnitskaya

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