Parenteral Antipsychotic Choice and Its Association With Emergency Department Length of Stay for Acute Agitation Secondary to Alcohol Intoxication

Academic Emergency Medicine : Official Journal of the Society for Academic Emergency Medicine
Jon B ColeMarc L Martel

Abstract

Acute agitation secondary to alcohol intoxication frequently requires parenteral sedatives for patient and caregiver safety. Antipsychotics play a prominent role; however, no consensus exists regarding the ideal agent. One important consideration when evaluating the choice of antipsychotic is its association with emergency department (ED) length of stay (LOS). We sought to determine the median ED LOS for patients receiving a single parenteral dose of an antipsychotic for acute agitation secondary to alcohol intoxication in an urban Level I trauma center. This was a retrospective review of patients receiving a single parenteral dose of droperidol, haloperidol, or olanzapine who were acutely intoxicated on alcohol from 2011 to 2016. Patients needing psychiatric assessment in our ED are discharged to a geographically separate department; thus, ED LOS is minimally impacted by waits for psychiatric assessment. Data were abstracted from the electronic medical record and are presented descriptively. A total of 40,601 patients were identified and screened; 24,319 patients were intoxicated but received no sedation. Of those remaining 4,495 received multiple drugs and/or benzodiazepines leaving 11,787 for analysis. Median age was 42 year...Continue Reading

References

Mar 27, 2003·Annals of Emergency Medicine·Louise W KaoStephen H Rosenfeld
Jun 26, 2003·The Journal of Clinical Psychiatry·Scott W Woods
Nov 12, 2005·Academic Emergency Medicine : Official Journal of the Society for Academic Emergency Medicine·Marc MartelMichelle Biros
Jul 22, 2010·European Psychiatry : the Journal of the Association of European Psychiatrists·C U Correll
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Jul 20, 2017·Therapeutics and Clinical Risk Management·Marco SolmiAndré F Carvalho
Aug 29, 2017·Annals of Emergency Medicine·Lauren R KleinMarc L Martel

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Citations

Feb 5, 2019·Clinical Toxicology : the Official Journal of the American Academy of Clinical Toxicology and European Association of Poisons Centres and Clinical Toxicologists·Lauren R KleinMarc L Martel
Dec 15, 2018·Academic Emergency Medicine : Official Journal of the Society for Academic Emergency Medicine·Jon B ColeMichael P Wilson
Sep 6, 2020·Academic Emergency Medicine : Official Journal of the Society for Academic Emergency Medicine·Marc L MartelJon B Cole

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