PMID: 3757780Sep 1, 1986Paper

Parenteral benzyl alcohol-induced hypersensitivity reaction

Drug Intelligence & Clinical Pharmacy
J P WilsonM S Edwards

Abstract

An uncommon hypersensitivity reaction due to parenteral benzyl alcohol administration is reported. One patient treated with benzyl alcohol-preserved cytarabine, vincristine, and heparin solutions developed a systemic hypersensitivity reaction on three separate occasions. Hypersensitivity to benzyl alcohol was confirmed by skin testing. Clinically, the patient presented with a fever and a maculopapular rash on the chest and arms. None of the reactions were life-threatening or required hospitalization of the patient.

References

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Citations

May 1, 1988·Medical Toxicology and Adverse Drug Experience·L K GolightlyB H Rumack
Mar 6, 2018·Anesthesia and Analgesia·Mark A Burbridge, Richard A Jaffe
Jul 7, 2020·EFSA Journal·UNKNOWN EFSA Panel on Food Additives and Flavourings (FAF)Maria Jose Frutos Fernandez
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Jul 16, 2014·The International Journal of Cardiovascular Imaging·Shaun CardozoLuis Afonso
Apr 10, 2019·Journal of Oncology Pharmacy Practice : Official Publication of the International Society of Oncology Pharmacy Practitioners·Manjusha SajithSandip Bartakke
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Jan 1, 1987·Cancer Metastasis Reviews·R B Weiss, J R Baker
Jul 15, 2021·Case Reports in Anesthesiology·Michael TrippRamon Go

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