Parenteral nutrition-associated hyperglycemia in noncritically ill inpatients is associated with higher mortality.

Canadian Journal of Gastroenterology = Journal Canadien De Gastroenterologie
Sofia SarkisianMaitreyi Raman

Abstract

Hyperglycemia is a marker of poor clinical outcomes in studies evaluating hospitalized critically ill patients. To identify whether glycemic control is associated with health outcomes including acute coronary events, renal failure, infection, hospital length of stay, intensive care unit (ICU) admission, sepsis and mortality in noncritically ill patients administered parenteral nutrition (PN), and to compare the current standard of care for glucose monitoring at the Foothills Medical Centre (Calgary, Alberta) with the 2009 American Society of Parenteral and Enteral Nutrition guidelines. A retrospective chart review of 100 adult (18 years of age or older) non-ICU inpatients who received PN for seven days or longer at the Foothills Medical Centre was conducted. Seventeen patients (17%) had a mean blood glucose level of 10.0 mmol/L or greater. PN patients with a mean blood glucose level of 10 mmol/L or greater had a higher rate of mortality than patients with a mean blood glucose level of less than 10 mmol/L (OR 7.22; 95% CI 1.08 to 48.29; P=0.042). Hyperglycemia was independently and significantly associated with mortality when adjusted for age and sex. Acute coronary events, renal failure, infection, hospital length of stay, vent...Continue Reading

Citations

May 18, 2011·Hospital Practice·Francisco J PasquelGuillermo E Umpierrez
Jul 4, 2012·JPEN. Journal of Parenteral and Enteral Nutrition·M Molly McMahonUNKNOWN American Society for Parenteral and Enteral Nutrition
Oct 16, 2012·Current Diabetes Reports·Aidar R Gosmanov, Guillermo E Umpierrez
Aug 26, 2014·Endocrine Practice : Official Journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists· Study Group Of Hyperglycemia In Parenteral Nutrition Nutrition Area Of The Spanish Society Of Endocrinology And Nutrition SeMaría C Tous
Jun 25, 2020·Nutrition in Clinical Practice : Official Publication of the American Society for Parenteral and Enteral Nutrition·Diana M SolomonAngela L Bingham
Apr 5, 2011·Journal of Veterinary Internal Medicine·Y QueauA J Fascetti
Nov 26, 2013·Diabetes, Obesity & Metabolism·H Thabit, R Hovorka
Feb 14, 2017·Journal of Translational Internal Medicine·Juan José Marín-PeñalverFrancisco Javier Del Cañizo-Gómez
Jun 13, 2019·JPEN. Journal of Parenteral and Enteral Nutrition·Dominick CurryDonald C Vickers
Sep 10, 2011·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Shougen CaoYu Li
Mar 14, 2018·Nutrition in Clinical Practice : Official Publication of the American Society for Parenteral and Enteral Nutrition·Ashley RatliffRocio Lopez
Aug 10, 2017·JPEN. Journal of Parenteral and Enteral Nutrition·Adam McCullochJeremy M Woodward
May 5, 2018·Diabetes Therapy : Research, Treatment and Education of Diabetes and Related Disorders·Analía RamosAntonio Pérez
May 26, 2017·Nutrition in Clinical Practice : Official Publication of the American Society for Parenteral and Enteral Nutrition·Diana M SolomonAngela L Bingham
Jan 26, 2021·Clinical Nutrition ESPEN·Muhamad Aizuddin RoszaliNurul Ain Mohd Tahir

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