PMID: 6403731Jan 1, 1983Paper

Parenteral nutrition in anuria of infancy: evidence for sustained net protein synthesis

JPEN. Journal of Parenteral and Enteral Nutrition
J Takala, M Kekomäki

Abstract

The effects of total parenteral nutrition were studied in two anuric neonates and an anuric infant. Based on the observations of urea production, nitrogen balance, and serum osmolality, the bulk of the infused nitrogen appeared to be incorporated into the body proteins. The need for potassium, calcium, phosphorous, and magnesium substitution was also indicative of net anabolism. Despite effective utilization of the amino acids, high plasma levels of phenylalanine and methionine, and extremely low levels of the urea cycle intermediates were measured. We conclude that the application of carefully planned parenteral nutrition may aid in the management of newborns with failing kidneys and that it influences considerably the indications of dialysis in early infancy.

References

Oct 1, 1978·The American Journal of Clinical Nutrition·M J BlumenkrantzS G Massry
Oct 1, 1978·The American Journal of Clinical Nutrition·M A HollidayJ Ramirez
Oct 1, 1978·The American Journal of Clinical Nutrition·P FürstJ Bergström
Jul 1, 1977·The American Journal of Clinical Nutrition·L J FilerB Chandramouli
Jan 1, 1980·JPEN. Journal of Parenteral and Enteral Nutrition·K J MotilW E Grupe
Feb 1, 1981·Journal of Pediatric Surgery·M Kekomäki

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