Parietal Involvement in Constructional Apraxia as Measured Using the Pentagon Copying Task

Dementia and Geriatric Cognitive Disorders
Stefan Van der Stigchelon behalf of the Utrecht Vascular Cognitive Impairment (VCI) Study Group

Abstract

Deficits in copying ("constructional apraxia") is generally defined as a multifaceted deficit. The exact neural correlates of the different types of copying errors are unknown. To assess whether the different categories of errors on the pentagon drawing relate to different neural correlates, we examined the pentagon drawings of the MMSE in persons with subjective cognitive complaints, mild cognitive impairment, or early dementia due to Alzheimer's disease. We adopted a qualitative scoring method for the pentagon copy test (QSPT) which categorizes different possible errors in copying rather than the dichotomous categories "correct" or "incorrect." We correlated (regional) gray matter volumes with performance on the different categories of the QSPT. Results showed that the total score of the QSPT was specifically associated with parietal gray matter volume and not with frontal, temporal, and occipital gray matter volume. A more fine-grained analysis of the errors reveals that the intersection score and the number of angles share their underlying neural correlates and are associated with specific subregions of the parietal cortex. These results are in line with the idea that constructional apraxia can be attributed to the failure ...Continue Reading

Citations

Dec 11, 2019·Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology·Luigi Trojano
Mar 23, 2021·Therapeutic Advances in Neurological Disorders·Michela LeocadiFederica Agosta
Aug 4, 2019·Cortex; a Journal Devoted to the Study of the Nervous System and Behavior·Antonia F Ten BrinkStefan Van der Stigchel
Jan 28, 2022·Brain Imaging and Behavior·Shuwei BaiYangtai Guan

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