Parkinsonian syndrome as a neurological manifestation of Behçet's disease

The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques
D BogdanovaD Georgiev

Abstract

The central nervous system is often involved in Behcet's disease. Most common are meningoencephalitic and brain stem syndromes. Although basal ganglia involvement is not an uncommon finding on necropsy, there are only single reports on extrapyramidal syndromes-dyskinesia, chorea and Parkinsonism in patients with Behcet's disease. We report a patient fulfilling the criteria of the International Study Group for Behcet's disease. He had recurrent oral ulcerations, bilateral posterior uveitis and retinal vasculitis, skin papules and pustules, and recurrent monoarthritis. Neurologic examination revealed pseudobulbar palsy, slight and asymmetric bilateral pyramidal syndrome, muscle rigidity involving the four limbs, bradykinesia, masked face, and impaired postural reflexes. There was postural tremor in the extremities and myoclonic jerks involving the tongue and face muscles. Magnetic resonance imaging demonstrated small bilateral multifocal hyperintense lesions, with right predilection, involving the periventricular white matter, brain stem and basal ganglia. The Parkinsonian syndrome found in our patient might be due to involvement of both substantia nigra and basal ganglia. This case further emphasizes the wide spectrum of the neu...Continue Reading

References

Jan 1, 1992·Current Eye Research·A M KlokA Kijlstra
Mar 1, 1989·Archives of Neurology·P SerdaroğluE Aktin
Feb 1, 1986·Neurology·R J Elble
Jan 1, 1982·Journal of Neurology·G BussoneP Giovannini
Nov 1, 1982·Arthritis and Rheumatism·E M TanR J Winchester
Aug 1, 1995·Postgraduate Medical Journal·M D BoggildJ R Heron
May 1, 1995·Journal of Neurology·F G Akman-DemirO Aral
Jul 1, 1993·Journal of Neurology, Neurosurgery, and Psychiatry·B WechslerP Godeau
Jan 1, 1993·European Neurology·U Hadar, F C Rose
Jul 1, 1996·Archives of Neurology·G Akman-DemirE Aktin

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Citations

Dec 4, 2019·Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova·V D PivenN A Totolyan
Mar 1, 2005·The Neurologist·Afshin Borhani HaghighiAli-Reza Nikseresht
Jun 6, 2008·Journal of Clinical Rheumatology : Practical Reports on Rheumatic & Musculoskeletal Diseases·Toshiaki KogureKoich Okamoto
Apr 7, 2009·Expert Review of Neurotherapeutics·Afshin Borhani Haghighi
May 24, 2019·Journal of the European Academy of Dermatology and Venereology : JEADV·Y B LeeY G Park
Jun 19, 2010·Internal Medicine·Fumitoshi NiwaMasanori Nakagawa
Jul 29, 2000·Seminars in Pediatric Neurology·N F Schor
Jan 24, 2009·Lancet Neurology·Adnan Al-Araji, Desmond P Kidd

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Basal ganglia in Parkinson's disease (MDS)

The basal ganglia is comprised of the neostriatum, the external and internal pallidal segments, the subthalamic nucleus, the substantia nigra pars reticulata, and the pars compacta of the substantia nigra. The basal ganglia circuitry is responsible for the correct execution of voluntary movements and is implicated in Parkinson's disease. Here is the latest research investigating the basal ganglia in Parkinson's disease.

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