Parkinson's disease and narcolepsy-like symptoms

Sleep Medicine
Ari YlikoskiMarkku Partinen

Abstract

Various sleep-related problems, for example, insomnia and symptoms of rapid eye movement behavior disorder (RBD), are common in patients with Parkinson's disease (PD). We studied the prevalence of symptoms of narcolepsy (NARC), hallucinations, and RBD and their association with other symptoms. Altogether, 1447 randomly selected patients with PD, aged 43-89 years, participated in a questionnaire study. A structured questionnaire with 207 items was based on the Basic Nordic Sleep Questionnaire. Questions on demographics, PD, RBD, and other issues were included. The response rate was 59.0%; of these patients, 73% had answered to all questions that were used in the analyses (N = 623). The occurrence of suspected narcolepsy (Ullanlinna Narcolepsy Scale ≥ 14 and Epworth Sleepiness Scale ≥ 11) was observed in 9.3% of the subjects (PD with NARC), RBD (REM Sleep Behavior Disorder Screening Questionnaire ≥ 6) in 39.2% of all patients with PD, and in 62.1% of those with PD and NARC. In patients with PD, hallucinations before going to bed in the evening occurred in 5.8%, hypnagogic hallucinations in 4.0%, hallucinations during night 8.3%, and hypnopompic hallucinations in 3.2%. Cataplexy symptoms occurred in 43.1% of subjects with PD and N...Continue Reading

References

Jun 1, 1995·Journal of Sleep Research·M Partinen, T Gislason
Feb 2, 2002·JAMA : the Journal of the American Medical Association·Douglas E HobsonJonathan Fleming
Apr 10, 2002·Neurology·I ArnulfY Agid
Oct 23, 2002·Brain : a Journal of Neurology·Antony J HardingGlenda M Halliday
Jun 11, 2003·Neurology·S A FactorUNKNOWN Parkinson Study Group
Aug 27, 2003·Neurology·X DrouotM P d'Ortho
Apr 28, 2005·Sleep Medicine·S NightingaleA J Williams
May 2, 2007·Brain : a Journal of Neurology·Rolf FronczekDick F Swaab
May 11, 2007·Brain : a Journal of Neurology·Thomas C ThannickalJerome M Siegel
Sep 27, 2007·Movement Disorders : Official Journal of the Movement Disorder Society·Karin Stiasny-KolsterWolfgang H Oertel
Jul 16, 2008·Parkinsonism & Related Disorders·Jens Carsten MöllerUlrich Hemmeter
Aug 11, 2010·Archives of Neurology·Elin B ForsaaGuido Alves
Oct 22, 2010·Neurology·Christopher G GoetzGlenn T Stebbins
Apr 14, 2011·Sleep Medicine·Smaranda Leu-SemenescuIsabelle Arnulf
Sep 16, 2011·Parkinsonism & Related Disorders·S Rios RomenetsR B Postuma
Jan 11, 2012·Journal of Neural Transmission·Chadwick W ChristineJill L Ostrem
Jan 24, 2012·Lancet Neurology·Sebastian J CrutchNick C Fox
May 23, 2014·Lancet Neurology·Markku PartinenOuti Vaarala

❮ Previous
Next ❯

Citations

Dec 29, 2016·Journal of Neural Transmission·Nataliya TitovaK Ray Chaudhuri
Jan 15, 2017·Chest·Jagan A Pillai, James B Leverenz
Oct 23, 2018·Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova·O V YakovlevaM G Poluektov
Jun 25, 2019·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·Ambra Stefani, Birgit Högl
Jun 13, 2017·Movement Disorders : Official Journal of the Movement Disorder Society·Nataliya Titova, K Ray Chaudhuri
Nov 5, 2019·Frontiers in Neurology·Cristian Falup-PecurariuK Ray Chaudhuri
Feb 28, 2021·Parkinsonism & Related Disorders·Fei FengHuiFang Shang

❮ Previous
Next ❯

Related Concepts

Related Feeds

Anxiety Disorders

Discover the latest research on anxiety disorders including agoraphobia, panic disorder, obsessive-compulsive disorder, and post-traumatic stress disorder here.

Basal Forebrain- Circuits

Basal forebrain is a region in the brain important for production of acetylcholine and is the major cholinergic output of the CNS. Discover the latest research on circuits in the basal forebrain here.

Related Papers

European Neurology
Ari YlikoskiMarkku Partinen
Neurologia i neurochirurgia polska
Aleksandra WierzbickaWojciech Jernajczyk
Zhonghua er ke za zhi. Chinese journal of pediatrics
Hu-sheng WuChun-hong Chen
Current Opinion in Neurology
Isabelle ArnulfDelphine Oudiette
© 2021 Meta ULC. All rights reserved