PMID: 12770667May 29, 2003Paper

Paroxysmal dyskinesias in childhood

Pediatric Neurology
Giovanna ZorziN Nardocci

Abstract

We report on clinical features of a large series of patients with paroxysmal dyskinesias. Fourteen patients had paroxysmal kinesigenic dyskinesia, with a mean age at onset of 7.1 years. In thirteen children the condition was idiopathic and nine of them had a positive family history; the remaining one had a Chiari malformation. Response to antiepileptic drugs was good in 60% of the treated patients. Six children had paroxysmal non-kinesigenic dyskinesia, with a mean age at onset of 8.1 years. Five children were symptomatic because of cerebral palsy (two patients), basal ganglia stroke (one patient), and acute inflammatory encephalopathy (one patient); the remaining patient's condition was familial with autosomal-dominant mode of inheritance. Response to medical treatment was unsuccessful contrasting with paroxysmal kinesigenic dyskinesia. Six children had paroxysmal exercise-induced dyskinesia, with a mean age at onset of 5 years. Their condition was idiopathic, with a positive family history in four. Two of these patients had also rolandic epilepsy and writer's cramp, and the syndrome had been previously mapped to chromosome 16. Although there have been great advances in the genetics of paroxysmal dyskinesias in which an ion ch...Continue Reading

References

Feb 1, 1991·Neurology·M H Saint HilaireS Fahn
Apr 1, 1986·Journal of Neurology, Neurosurgery, and Psychiatry·E LugaresiP Montagna
May 1, 1987·Journal of Neurology, Neurosurgery, and Psychiatry·H J BergerE M Joosten
Jul 1, 1973·Neurology·S S JungJ A Brody
Jun 1, 1966·Brain : a Journal of Neurology·R L Hudgins, K B Corbin
Oct 1, 1995·Annals of Neurology·M Demirkiran, J Jankovic
Jul 1, 1996·Movement Disorders : Official Journal of the Movement Disorder Society·C CosentinoJ M Cuba
Nov 1, 1996·Movement Disorders : Official Journal of the Movement Disorder Society·D E Riley
Feb 1, 1996·Yonsei Medical Journal·I S ChoiW Y Jung
Dec 17, 1997·Movement Disorders : Official Journal of the Movement Disorder Society·K P BhatiaC D Marsden
Nov 21, 1998·Clinical Neurology and Neurosurgery·L C TanH Tjia
Apr 9, 1999·Journal of Neurology·M K HouserC D Marsden
May 14, 1999·Journal of Neurology·K P Bhatia
Jun 4, 1999·Brain : a Journal of Neurology·F ProviniP Montagna
Dec 1, 1999·American Journal of Human Genetics·H a TomitaN Niikawa
Nov 15, 2000·Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology·L MargariP Ventura
Aug 2, 2001·Movement Disorders : Official Journal of the Movement Disorder Society·T PerniolaG Illiceto
Aug 25, 2001·Epilepsia·R Guerrini

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Citations

Jul 29, 2011·Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology·Tiziana Granata, Laura Grazia Valentini
Jan 23, 2009·Revista de neurologia·A B Perona-MoratallaS García-Muñozguren
Nov 26, 2015·Brain : a Journal of Neurology·Alice R GardinerHenry Houlden
Mar 18, 2016·Seizure : the Journal of the British Epilepsy Association·Feng LiNeha D Poonit
Mar 24, 2009·Pediatric Neurology·Kipp L Chillag, Steven T Deroos
Oct 22, 2008·Revue neurologique·H Mrabet KhiariA Mrabet
Jan 31, 2012·Developmental Medicine and Child Neurology·Carlotta CanaveseNardo Nardocci
Jun 1, 2011·Movement Disorders : Official Journal of the Movement Disorder Society·Kailash P Bhatia
Oct 26, 2005·Neurobiology of Disease·Brandy E Fureman, Ellen J Hess
Apr 12, 2005·Epilepsy & Behavior : E&B·Zhongzeng LiGigi Smith
Aug 4, 2012·The International Journal of Neuroscience·Yi YangMeiping Ding
Aug 28, 2016·Revue neurologique·A Méneret, E Roze
Apr 29, 2005·Movement Disorders : Official Journal of the Movement Disorder Society·Michael H PourfarSteven J Frucht
Apr 15, 2009·Current Treatment Options in Neurology·Shyamal H MehtaKapil D Sethi

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