Paroxysmal head drops with ataxia-like symptoms presenting as Sandifer syndrome in a 3-year old girl

BMJ Case Reports
Abubakar SharifHimadri Chakraborty

Abstract

We present a case of Sandifer syndrome in a 3-year-old girl who initially presented with a history of recurrent paroxysmal head drops associated with ataxia-like symptoms and recurrent falls sustaining a clavicular fracture on one occasion. She was referred to and seen by the paediatric neurologist. Physical examination, electroencephalogram, MRI brain, electromyograph single fibre study and blood tests were all normal. With the history of hiccups and choking-like episodes she was referred to the speech and language therapist (SALT). SALT assessment did not reveal indications of swallowing impairment or possible aspiration. A barium swallow later showed small amount of reflux into the distal oesophagus. This prompted a trial of lansoprazole and she was referral to the gastroenterologists. Endoscopy and oesophageal manometry were essentially normal. However, the pH impedance study revealed severe gastro-oesophageal reflux disease. She continued with lansoprazole and dairy-free diet and her symptoms resolved.

References

May 1, 1979·The Journal of Pediatrics·J M Sondheimer, B A Morris
May 1, 1977·American Journal of Diseases of Children·W J Murphy, S S Gellis
Sep 1, 1989·Archives of Disease in Childhood·J W PuntisI W Booth
Dec 1, 1985·Developmental Medicine and Child Neurology·C S Nanayakkara, J Y Paton
Aug 1, 1982·Thorax·C J Smallpiece, P B Deverall
Jun 1, 1980·Developmental Medicine and Child Neurology·S L WerlinR C Arndorfer
Aug 1, 1995·European Journal of Pediatric Surgery : Official Journal of Austrian Association of Pediatric Surgery ... [et Al] = Zeitschrift Für Kinderchirurgie·P GorrotxategiM Barriola
Sep 30, 2000·American Journal of Perinatology·G CorradoE Cardi
Nov 21, 2001·Clinical Neurology and Neurosurgery·M ShahnawazR F Gledhill
Oct 3, 2002·Pediatrics·Prakash KotagalBarbara Wolgamuth
May 16, 1964·Lancet·M KINSBOURNE
Apr 15, 2006·Digestive Diseases and Sciences·Eric A FrankelSusan R Orenstein
Dec 16, 2006·Pediatrics International : Official Journal of the Japan Pediatric Society·Nimet Kabakuş, Abdullah Kurt
Jul 20, 2007·European Journal of Pediatric Surgery : Official Journal of Austrian Association of Pediatric Surgery ... [et Al] = Zeitschrift Für Kinderchirurgie·N LehwaldW T Knoefel
Sep 1, 2008·Therapeutic Advances in Neurological Disorders·Iris Unterberger, Eugen Trinka
Mar 14, 2012·Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology·Abdul Qayyum RanaSaliman Joian
Aug 15, 2013·Journal of Laparoendoscopic & Advanced Surgical Techniques. Part a·Steven S Rothenberg
Oct 1, 2014·Movement Disorders Clinical Practice·Ana Cecilia SanguinettiEmilia Mabel Gatto

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