Partial adrenalectomy: the National Cancer Institute experience

Urology
Eric K DinerMcClellan M Walther

Abstract

To report our experience of partial adrenalectomy and demonstrate whether adrenal function can be preserved in patients with hereditary adrenal pheochromocytoma. Total adrenalectomy has largely been used in the treatment of patients with hereditary adrenal pheochromocytomas. Adrenal cortical-sparing surgery is an alternative approach that aims to balance tumor removal with preservation of adrenocortical function. From 1995 to 2004, 33 patients with hereditary pheochromocytoma presented with adrenal masses. Partial adrenalectomy (open or laparoscopic) was performed if normal adrenocortical tissue was evident on preoperative imaging or intraoperative ultrasonography. Various operative parameters, as well as postoperative function of the residual adrenal remnants, were determined. Of the 33 patients, 8 underwent open partial adrenalectomy and 25 laparoscopic partial adrenalectomy during a 10-year period. Ten patients underwent simultaneous, bilateral partial adrenalectomy and 8 underwent surgery on a solitary adrenal gland, 4 of whom received postoperative steroid replacement (stopped in 3 after 1 to 3 months). All other patients had normal catecholamine levels and remained tumor free by imaging at a mean follow-up of 36 months (r...Continue Reading

References

Jan 1, 1989·Immunopharmacology and Immunotoxicology·L D ButlerA M Bendele
Feb 23, 1999·The British Journal of Surgery·H P NeumannG Kirste
Mar 30, 1999·World Journal of Urology·M M WaltherW M Linehan
Jun 7, 2000·The Journal of Urology·M M WaltherW M Linehan

❮ Previous
Next ❯

Citations

Feb 12, 2011·Updates in Surgery·Giuseppe CavallaroGiorgio De Toma
Jul 27, 2014·European Journal of Endocrinology·Eleonora P Corssmit, Johannes A Romijn
May 6, 2014·Current Hypertension Reports·Joseph M PappachanFahmy W Hanna
Jul 9, 2009·Current Opinion in Urology·Jonathan A Coleman, Paul Russo
Oct 5, 2007·Reviews in Endocrine & Metabolic Disorders·William F Young
Jun 21, 2008·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Bas HavekesKarel Pacak
Sep 11, 2013·Surgical Endoscopy·Dimitrios StefanidisUNKNOWN Society of Gastrointestinal and Endoscopic Surgeons
Apr 11, 2009·Journal of Endourology·Angelish KumarMichael D Stifelman
Jun 1, 2012·Journal of Robotic Surgery·Volkan GencEren Berber
Jul 12, 2008·Annals of Surgical Oncology·Shih-Ping ChengGerard M Doherty
Jan 16, 2009·Der Chirurg; Zeitschrift für alle Gebiete der operativen Medizen·M K Walz
Oct 1, 2011·Journal of Pediatric Urology·Roberto Iglesias LopesMiguel Srougi
Dec 3, 2010·Urology·Ronald S BorisGennady Bratslavsky
Dec 1, 2010·Best Practice & Research. Clinical Endocrinology & Metabolism·Pierre-François PlouinCharlotte Lepoutre
Oct 1, 2010·The Journal of Urology·Peter A Pinto
Sep 8, 2010·Hematology/oncology Clinics of North America·David J GallagherJonathan A Coleman
Jun 16, 2010·The Journal of Urology·Deborah R KayeGennady Bratslavsky
Nov 11, 2008·The Urologic Clinics of North America·Jonathan A Coleman
Nov 17, 2007·American Journal of Surgery·Andrew D LudwigDarrell L Cass
Apr 3, 2009·BJU International·Chun-Hou LiaoShih-Chieh Chueh
Nov 15, 2006·Annals of the New York Academy of Sciences·Paul A FitzgeraldKatherine K Matthay
Apr 20, 2007·BJU International·Manish A ViraW Marston Linehan
May 16, 2012·International Journal of Urology : Official Journal of the Japanese Urological Association·Soichi Mugiya
Nov 18, 2009·The British Journal of Surgery·B-J PetriR R de Krijger
Sep 19, 2006·Best Practice & Research. Clinical Endocrinology & Metabolism·Pierre-François Plouin, Anne-Paule Gimenez-Roqueplo
Jan 30, 2014·Maturitas·A TsirlinM A Banerji
Feb 15, 2015·International Journal of Surgery·Vinayak NagarajaSenarath Edirimanne
Jan 13, 2015·Current Opinion in Urology·Daniela Colleselli, Günter Janetschek
Feb 7, 2015·Urology Annals·Imran K JalbaniFarhat Abbas
Dec 6, 2008·Current Opinion in Urology·Elias S Hyams, Michael D Stifelman
Jul 12, 2019·World Journal of Urology·Chen YeBo Yang
Jan 28, 2017·Indian Journal of Surgical Oncology·Hattangadi Sanjay Bhat, Balagopal Nair Tiyadath
Dec 12, 2019·Minimally Invasive Therapy & Allied Technologies : MITAT : Official Journal of the Society for Minimally Invasive Therapy·Altug TuncelOzer Guzel
Sep 1, 2010·Journal of Robotic Surgery·Jennifer YatesRavi Munver

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.