Partial atrioventricular septal defect in the fetus: diagnostic features and associations in a multicenter series of 30 cases

Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology
D PaladiniC Nappi

Abstract

To assess the anatomical features and the associations of partial atrioventricular septal defect (pAVSD) in the fetus. This was a retrospective multicenter study of 30 cases of confirmed pAVSD seen since 1996 at two referral centers. The following variables were available for analysis in all cases: indications for fetal echocardiography, diagnostic features, associated cardiac, extracardiac and chromosomal anomalies and fetoneonatal outcome. At fetal echocardiography, the echocardiographic features deemed indicative of pAVSD were: 1) ostium primum atrial septal defect and 2) loss of the normal offset appearance of the atrioventricular valves. Eighteen of the 30 (60%) cases were diagnosed before 24 weeks of gestation and 12 were diagnosed later. Suspicion of congenital heart disease and known aneuploidy (trisomy 21) accounted for 60% of the referral indications. The two anatomical landmarks deemed indicative of pAVSD were detected in all cases at echocardiography. Twelve cases were isolated (one with increased nuchal transluceny at the 12-week scan, one with polyhydramnios, one with fetal growth restriction) including four that were detected on routine ultrasound examination by the authors. Additional cardiac anomalies were pres...Continue Reading

References

Aug 1, 1997·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·J K ParkD R Towner
Nov 5, 1999·Obstetrics and Gynecology·M F DelisleD F Farquharson
Nov 16, 1999·American Journal of Obstetrics and Gynecology·L D Allan
Aug 10, 2000·Journal of the American College of Cardiology·I C HuggonG K Sharland
Nov 18, 2003·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·J-M JouannicD Bonnet
Jul 9, 2004·Cardiology in the Young·Kathryn A DunlopDennis J Gladstone
Jul 24, 2007·The Annals of Thoracic Surgery·Karl F WelkeRoss M Ungerleider

❮ Previous
Next ❯

Citations

Mar 15, 2021·European Journal of Obstetrics, Gynecology, and Reproductive Biology·Martin MetzenbauerErich Hafner

❮ Previous
Next ❯

Related Concepts

Related Feeds

Aortic Coarctation

Aortic coarctation is a congenital condition characterized by narrowing of the aorta. Discover the latest research on this disease here.

Birth Defects

Birth defects encompass structural and functional alterations that occur during embryonic or fetal development and are present since birth. The cause may be genetic, environmental or unknown and can result in physical and/or mental impairment. Here is the latest research on birth defects.

Related Papers

Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology
S-J YooJ Smallhorn
Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology
C BergU Gembruch
© 2021 Meta ULC. All rights reserved