PMID: 9537471Apr 16, 1998Paper

Partial atrophy in prostate needle cores: another diagnostic pitfall for the surgical pathologist

The American Journal of Surgical Pathology
J R OppenheimerJonathan I Epstein

Abstract

We have seen in consultation a variant of atrophy, which is frequently confused with well-differentiated adenocarcinoma of the prostate. We have designated this entity as partial atrophy to distinguish it from its more common counterpart of fully developed atrophy. Partial atrophy is defined as benign prostate glands with relatively scant cytoplasm, yet the glands are not fully atrophic in that they do not appear basophilic at low magnification. Fifty-one cases of partial atrophy were identified (4 from Johns Hopkins Hospital, 47 from consultation). Within the partial atrophy focus, irregular (crinkled) nuclei were frequent in 23.5% and occasionally present in 33.3% of cases. Visible nucleoli were frequent in 25.4% of cases. Basal cells were not identifiable in 27.4% of cases or were hard to identify in 35.3% of cases. No intraluminal crystalloids or blue-tinged mucinous secretion was identified in partial atrophy. Adenocarcinoma or glands suspicious for cancer were present in other cores in 15.6% of cases. More fully developed atrophy was present in simultaneously obtained needle cores in 35.3% of cases. In the cases in which regular atrophy was the only coexisting condition, it was present within one 10x field from the partia...Continue Reading

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Citations

Aug 4, 2001·International Journal of Surgical Pathology·D B Troxel
Jul 14, 2007·International Braz J Urol : Official Journal of the Brazilian Society of Urology·Athanase BillisUbirajara Ferreira
Apr 15, 2008·The American Journal of Surgical Pathology·Wenle WangJonathan I Epstein
Jan 4, 2018·Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc·Kiril Trpkov
Jul 29, 2003·The American Journal of Surgical Pathology·Cristina Magi-GalluzziJonathan I Epstein
Sep 27, 2006·The American Journal of Surgical Pathology·Angelo M De MarzoM S Lucia
Apr 3, 2010·Virchows Archiv : an International Journal of Pathology·Athanase BillisLeandro L L Freitas
Jul 16, 2011·American Journal of Clinical Pathology·Xiaojun WuOmar Hameed
Aug 23, 2017·Critical Reviews in Clinical Laboratory Sciences·Francesca SanguedolceLuigi Cormio
Aug 6, 1999·The American Journal of Surgical Pathology·M B AminJ R Srigley
Feb 21, 2004·Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc·John R Srigley
Feb 27, 2004·BJU International·T H Van der KwastR F Hoedemaeker
Sep 8, 2010·International Braz J Urol : Official Journal of the Brazilian Society of Urology·Athanase Billis
Sep 25, 2008·The American Journal of Surgical Pathology·Tehmina Z Ali, Jonathan I Epstein
Mar 31, 2012·Archives of Pathology & Laboratory Medicine·Fadi Brimo, Jonathan I Epstein
Dec 12, 2018·The American Journal of Surgical Pathology·Luis BeltranUNKNOWN Transatlantic Prostate Group
Apr 3, 2020·International Journal of Surgical Pathology·Julian Arista-NasrJorge Albores-Saavedra
Nov 1, 2006·American Journal of Clinical Pathology·Brian P Adley, Ximing J Yang
Jan 5, 2000·BJU International·J L BurtonJ B Anderson
Jan 4, 2012·Histopathology·Rodolfo MontironiAntonio Lopez-Beltran
May 8, 2001·American Journal of Clinical Pathology·P Thorson, P A Humphrey
Dec 29, 2007·The American Journal of Surgical Pathology·Christopher G PrzybycinRajal B Shah
Oct 20, 2020·Pathology·Lars EgevadHemamali Samaratunga
Dec 14, 1999·The American Journal of Pathology·A M De MarzoW G Nelson
Mar 4, 2010·Archives of Pathology & Laboratory Medicine·Omar Hameed, Peter A Humphrey
Mar 4, 2006·Seminars in Diagnostic Pathology·Omar Hameed, Peter A Humphrey
Dec 1, 2008·Surgical Pathology Clinics·George J Netto, Jonathan I Epstein
Dec 1, 2008·Surgical Pathology Clinics·Ming Zhou, Cristina Magi-Galluzzi

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