Partial epileptic seizure with versive movements examined by [99m Tc] HM-PAO brain single photon emission computed tomography: an early post study analyzed by computerized brain atlas methods

Epilepsia
B WederT Vonesch

Abstract

The consecutive steps of a seizure with leftward versive movements of the head and eyes were analyzed after video monitoring and correlated with findings on single photon emission computed tomography (SPECT) using [99m Tc] hexamethyl propylene amine oxime (HM-PAO). Evaluation included reconstruction of subtraction images from the early postictal state, obtained immediately after the video-monitored seizure, and the interictal baseline. Based on normalized perfusion indexes within voxels of Talairach space, we concluded that the primary epileptogenic focus was in the premotor cortex of the contralateral hemisphere. We then placed the functional data in an anatomic context by adapting a dedicated computerized brain atlas (CBA) to the patient's brain with the aid of magnetic resonance imaging (MRI) slices. By inverse transformation, the patient's data were aligned with the standard geometry of the brain atlas for comparison purposes with data from the literature. The validated activation field projected exactly onto the right precentral sulcus with the anterior border zone including the right frontal eye field.

References

Jan 1, 1976·Transactions of the American Neurological Association·R C CollinsL Sokoloff
Aug 1, 1976·Archives of Neurology·R C CollinsF Plum
Jan 1, 1991·Journal of Computer Assisted Tomography·T GreitzL Eriksson
Mar 1, 1991·Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism·P T Fox
Jul 1, 1990·Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism·R J SeitzB Nordell
Oct 1, 1987·Neurology·R S McLachlan
Jul 1, 1985·Journal of Computer Assisted Tomography·M VanierG Salamon
Mar 1, 1966·Brain Research·M E Scheibel, A B Scheibel
Apr 1, 1983·Neurology·J EngelM Nuwer
Jan 12, 1994·Neuroreport·B Weder, R J Seitz
Jun 1, 1994·Brain : a Journal of Neurology·B WederR J Seitz
Jul 1, 1993·Journal of Computer Assisted Tomography·U KnorrR J Seitz
Apr 1, 1993·Journal of Neuroimaging : Official Journal of the American Society of Neuroimaging·R KuznieckyF Thomas

❮ Previous
Next ❯

Citations

Aug 30, 2002·Epilepsy Research·Fritz LeutmezerChristoph Baumgartner
Mar 5, 2003·Epilepsia·Chi Wan KooElissa L Kramer
Mar 10, 2000·Journal of Clinical Neurophysiology : Official Publication of the American Electroencephalographic Society·E L SoB P Mullan
Mar 20, 1999·Journal of Neurology, Neurosurgery, and Psychiatry·T J O'BrienC R Jack
Jul 14, 2000·Nuclear Medicine Communications·B H BrinkmannR A Robb
Mar 15, 2015·Epilepsy & Behavior : E&B·Metin MercanErhan Bilir
Jan 29, 1999·Journal of Neuroimaging : Official Journal of the American Society of Neuroimaging·S LanzingerC Fretz

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.