Jan 1, 1979

Partial purification and characterisation of bat liver ribonuclease. Hydrolysis of purine and pyrimidine polynucleotides by bat liver RNase

West African Journal of Pharmacology and Drug Research
J O FolayanE O Ngaha

Abstract

A ribonuclease has been extracted from bat liver and purified. From polyacrylamide gel electrophoresis, it was found that there is only one molecular weight unit in this enzyme and this has a molecular weight of about 28,000. This enzyme was found to hydrolyse both purine and pyrimidine polynucleotides (e.g. polyadenylic acid and polycytidylic acid respectively). Hydrolysis of polyadenylic acid was found to be faster than that of polycytidylic acid.

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Mentioned in this Paper

Polynucleotides
Alkaline Ribonuclease
Pancreatic ribonuclease
Pyrimidine
Purification Aspects
Pyrimidines
Polyacrylamide Gel Electrophoresis
Ribonucleases
Hydrolysis
RNASE1

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